Articles with "benzyloxy benzamides" as a keyword



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4-(Phenoxy) and 4-(benzyloxy)benzamides as potent and selective inhibitors of mono-ADP-ribosyltransferase PARP10/ARTD10.

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Published in 2018 at "European journal of medicinal chemistry"

DOI: 10.1016/j.ejmech.2018.06.047

Abstract: Human Diphtheria toxin-like ADP-ribosyltranferases (ARTD) 10 is an enzyme carrying out mono-ADP-ribosylation of a range of cellular proteins and affecting their activities. It shuttles between cytoplasm and nucleus and influences signaling events in both compartments,… read more here.

Keywords: potent selective; benzamides potent; artd10; phenoxy benzyloxy ... See more keywords