Base excision repair capacity as a determinant of prognosis and therapy response in colon cancer patients.
Sign Up to like & getrecommendations! Published in 2018 at "DNA repair"
DOI: 10.1016/j.dnarep.2018.09.006
Abstract: The DNA-damaging agent 5-fluorouracil represents the most commonly used chemotherapeutic drug for colorectal cancer patients. DNA lesions associated with 5-fluorouracil therapy are primarily repaired by base excision repair (BER) and mismatch repair (MMR) pathways. Published… read more here.
Keywords: response; ber drc; therapy; ber ... See more keywords