GW28-e0988 Berberine attenuates cardiac fibrosis via downregulating IGF1R in diabetic rats
Sign Up to like & getrecommendations! Published in 2017 at "Journal of the American College of Cardiology"
DOI: 10.1016/j.jacc.2017.07.131
Abstract: Diabetic cardiac fibrosis increases ventricular stiffness and facilitates occurrence of diastolic and systolic dysfunction. IGF 1R is a key receptor regulating cell growth, survival and differentiation. However, the role of IGF 1R and its downstream… read more here.
Keywords: fibrosis; e0988 berberine; gw28 e0988; cardiac fibrosis ... See more keywords
Berberine Attenuates Hyperglycemia by Inhibiting the Hepatic Glucagon Pathway in Diabetic Mice
Sign Up to like & getrecommendations! Published in 2020 at "Oxidative Medicine and Cellular Longevity"
DOI: 10.1155/2020/6210526
Abstract: Dysregulated glucagon drives hyperfunction in hepatic glucose output, which is the main cause of persistent hyperglycemia in type 2 diabetes. Berberine (Zhang et al., 2010) has been used as a hypoglycemic agent, yet the mechanism… read more here.
Keywords: glucagon; bbr; berberine attenuates; diabetic mice ... See more keywords