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   Articles with "bergenin" as a keyword



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Study on preparation and controlled release in vitro of bergenin-amino polylactic acid polymer.

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recommendations! Published in 2020 at "International journal of biological macromolecules"

DOI: 10.1016/j.ijbiomac.2020.02.205

Abstract: The efficacy of traditional tablets, drop pills and soft capsules of bergenin is far lower than expected. Therefore, bergenin was modified in this paper to connect with amino polylactic acid, a kind of biodegradable material,… read more here.

Keywords: amino polylactic; amino; bergenin; bergenin amino ... See more keywords
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Bergenin Exerts Hepatoprotective Effects by Inhibiting the Release of Inflammatory Factors, Apoptosis and Autophagy via the PPAR-γ Pathway

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recommendations! Published in 2020 at "Drug Design, Development and Therapy"

DOI: 10.2147/dddt.s229063

Abstract: Objective Hepatic ischemia reperfusion (IR) limits the development of liver transplantation technology. The aim of this study was to explore the protective effects of Bergenin on hepatic IR, particularly the elimination of reactive oxygen species… read more here.

Keywords: apoptosis autophagy; ppar pathway; bergenin; release ... See more keywords
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Bergenin of Peltophorum dubium (Fabaceae) Roots and Its Bioactive Semi‑Synthetic Derivatives

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recommendations! Published in 2020 at "Journal of the Brazilian Chemical Society"

DOI: 10.21577/0103-5053.20200141

Abstract: This work describes the isolation of pure bergenin from Peltophorum dubium roots with good yields and its further derivatization through Williamson synthesis. The alkyl derivatives of the bergenin were identified by nuclear magnetic resonance and… read more here.

Keywords: synthetic derivatives; bergenin; semi synthetic; peltophorum dubium ... See more keywords
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p62-Nrf2 Regulatory Loop Mediates the Anti-Pulmonary Fibrosis Effect of Bergenin

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recommendations! Published in 2022 at "Antioxidants"

DOI: 10.3390/antiox11020307

Abstract: Idiopathic pulmonary fibrosis (IPF) can severely disrupt lung function, leading to fatal consequences, and there is currently a lack of specific therapeutic drugs. Bergenin is an isocoumarin compound with lots of biological functions including antioxidant… read more here.

Keywords: bergenin; regulatory loop; pulmonary fibrosis; p62 ... See more keywords
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Bergenin Reduces Experimental Painful Diabetic Neuropathy by Restoring Redox and Immune Homeostasis in the Nervous System

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recommendations! Published in 2020 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms21144850

Abstract: Diabetic neuropathy is a frequent complication of diabetes. Symptoms include neuropathic pain and sensory alterations—no effective treatments are currently available. This work characterized the therapeutic effect of bergenin in a mouse (C57/BL6) model of streptozotocin-induced… read more here.

Keywords: redox immune; bergenin; painful diabetic; nervous system ... See more keywords