Articles with "bespoke screening" as a keyword



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Abstract 506: A bespoke screening platform to study mono(ADP-ribosylation)

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Published in 2020 at "Cancer Research"

DOI: 10.1158/1538-7445.am2020-506

Abstract: Mono(ADP-ribosylation) (MARylation) and poly(ADP-ribosylation) (PARylation) are post-translational modifications deposited on multiple amino acids by PARP enzymes using nicotinamide adenine dinucleotide (NAD+) as the ADP-ribose donating substrate. While there are approved drugs and clinical trials on-going… read more here.

Keywords: adp ribosylation; screening platform; bespoke screening; mono adp ... See more keywords