Articles with "best class" as a keyword



Firms reporting of sustainable development goals (SDGs): An empirical study of best‐in‐class companies

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Published in 2024 at "Sustainable Development"

DOI: 10.1002/sd.2944

Abstract: This article presents an empirical analysis of the non‐financial reporting of the United Nations Sustainable Development Goals (SDGs) by a sample of 24 best‐in‐class companies across various sectors worldwide. The sample was selected based on… read more here.

Keywords: development goals; best class; sustainable development; class companies ... See more keywords
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‘Best in class' socially responsible investment. The actual performance evaluation between the US and Europe

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Published in 2020 at "Journal of Sustainable Finance and Investment"

DOI: 10.1080/20430795.2020.1742012

Abstract: This study investigates the realized performance of socially responsible investments (SRIs) in US and in European financial markets. We simulate a real investment strategy based on continuous portf... read more here.

Keywords: investment; class socially; responsible investment; performance ... See more keywords

A “best-in-class” systemic biomarker predictor of clinically relevant knee osteoarthritis structural and pain progression

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Published in 2023 at "Science Advances"

DOI: 10.1126/sciadv.abq5095

Abstract: We aimed to identify markers in blood (serum) to predict clinically relevant knee osteoarthritis (OA) progression defined as the combination of both joint structure and pain worsening over 48 months. A set of 15 serum… read more here.

Keywords: best class; progression; clinically relevant; relevant knee ... See more keywords

Abstract C012: Discovery of a Best-in-Class small molecule p53 Y220C reactivator: Breaking through the potency ceiling

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Published in 2025 at "Molecular Cancer Therapeutics"

DOI: 10.1158/1535-7163.targ-25-c012

Abstract: The tumor suppressor p53 is inactivated in approximately 50% of human cancers. In about 1% of solid tumors, a specific Y220C point mutation induces p53 misfolding, leading to its inactivation. This mutation also creates a… read more here.

Keywords: potency; p53; p53 y220c; small molecule ... See more keywords

Abstract CT122: Phase I study of potentially "best-in-class" survivin-responsive conditionally replicating adenovirus for advanced sarcoma actually demonstrates potent and long-term efficacy and high safety

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Published in 2018 at "Clinical Trials"

DOI: 10.1158/1538-7445.am2018-ct122

Abstract: [Background] Recent approvals of oncolytic virus (OV) by FDA and EMA attract the worldwide oncologists and anticancer market. We developed the first platform technology to efficiently construct diverse types of a next-generation conditionally replicating adenovirus… read more here.

Keywords: cra; phase study; best class; efficacy ... See more keywords

Abstract LB299: Clinical pharmacokinetics and peripheral receptor occupancy of OR502, best-in-class antibody against leukocyte immunoglobulin-like receptor B2 (LILRB2), alone and in combination with cemiplimab

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Published in 2025 at "Cancer Research"

DOI: 10.1158/1538-7445.am2025-lb299

Abstract: Based on its single-agent clinical activity and excellent safety profile, OR502 has best-in-class properties. Preclinically, OR502 reverses and prevents myeloid cell-mediated immune suppression and restores T cell functions with superior activity than other antibodies targeting… read more here.

Keywords: or502 best; receptor; best class; receptor occupancy ... See more keywords

A Preliminary Study of BEST in CLASS–Elementary on Teacher Self-Efficacy, Burnout, and Attributions

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Published in 2021 at "Behavioral Disorders"

DOI: 10.1177/01987429211010672

Abstract: Student problem behaviors in early elementary school have been associated with increased teacher burnout, negative emotions, and stress, along with negative student outcomes, including increased risk of emotional and behavioral disorders (EBDs). This study examined… read more here.

Keywords: class; teacher self; self efficacy; efficacy burnout ... See more keywords