What Is the Best Disease-Guided Approach to Statin?
Sign Up to like & getrecommendations! Published in 2017 at "Journal of the American College of Cardiology"
DOI: 10.1016/j.jacc.2016.11.035
Abstract: Silverman et al. [(1)][1] report that in a meta-regression analysis, the use of statin and nonstatin therapies that act via upregulation of low-density lipoprotein (LDL) receptor expression to reduce LDL cholesterol (LDL-C) were associated with similar… read more here.
Keywords: cardiology; disease guided; statin; guided approach ... See more keywords
Generation of a human induced pluripotent stem cell line, BRCi005-A, derived from a Best disease patient with BEST1 mutations.
Sign Up to like & getrecommendations! Published in 2020 at "Stem cell research"
DOI: 10.1016/j.scr.2020.101782
Abstract: Best Disease is an inherited retinal dystrophy that results in progressive and irreversible central vision loss caused by mutations of BESTROPHIN1 (BEST1). We established human induced pluripotent stem cells (iPSCs) from a Best disease patient… read more here.
Keywords: human induced; disease; best1; induced pluripotent ... See more keywords
Best disease presenting as subretinal pigment epithelium hyperreflectivite lesion on spectral-domain optical coherence tomography: Multimodal imaging features.
Sign Up to like & getrecommendations! Published in 2021 at "European journal of ophthalmology"
DOI: 10.1177/11206721211055961
Abstract: PURPOSE To report clinical and multimodal imaging features of Best disease in patients presenting with subretinal pigment epithelium hyperreflective lesions. DESIGN Retrospective study. METHODS Clinical examination findings and multimodal imaging features, including color fundus photography,… read more here.
Keywords: best disease; multimodal imaging; subretinal pigment; pigment epithelium ... See more keywords
Induced Pluripotent Stem Cell Modeling of Best Disease and Autosomal Recessive Bestrophinopathy
Sign Up to like & getrecommendations! Published in 2020 at "Yonsei Medical Journal"
DOI: 10.3349/ymj.2020.61.9.816
Abstract: Purpose To understand the pathophysiology of Best disease (BD) and autosomal recessive bestrophinopathy (ARB) by establishing an in vitro model using human induced pluripotent stem cell (iPSC). Materials and Methods Human iPSC lines were generated… read more here.
Keywords: ipsc rpe; disease autosomal; ipsc; best disease ... See more keywords