T-bet-expressing B cells contribute to the autoreactive plasma cell pool in Lyn-/- mice.
Sign Up to like & getrecommendations! Published in 2023 at "European journal of immunology"
DOI: 10.1002/eji.202250300
Abstract: Systemic Lupus Erythematosus (SLE) is characterized by pathogenic autoantibodies against nucleic acid-containing antigens. Understanding which B cell subsets give rise to these autoantibodies may reveal therapeutic approaches for SLE that spare protective responses. Mice lacking… read more here.
Keywords: autoreactive plasma; cell; bet cells; lyn mice ... See more keywords
Expression Regulation and Function of T-Bet in NK Cells
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2021.761920
Abstract: Natural killer (NK) cells are cytotoxic innate lymphocytes that play an important role in immune surveillance. The development, maturation and effector functions of NK cells are orchestrated by the T-box transcription factor T-bet, whose expression… read more here.
Keywords: bet cells; function; expression; expression regulation ... See more keywords