Uptake and effects of the beta-adrenergic agonist salbutamol in fish: supporting evidence for the fish plasma model.
Sign Up to like & getrecommendations! Published in 2019 at "Environmental toxicology and chemistry"
DOI: 10.1002/etc.4543
Abstract: The fish plasma model (FPM) predicts the fish blood plasma concentration of a pharmaceutical from the water concentration to which the fish is exposed and compares it to the human therapeutic plasma concentration (Hther PC)… read more here.
Keywords: plasma model; plasma; fish plasma; adrenergic agonist ... See more keywords
Role of Beta-adrenergic Receptors and Sirtuin Signaling in the Heart During Aging, Heart Failure, and Adaptation to Stress
Sign Up to like & getrecommendations! Published in 2017 at "Cellular and Molecular Neurobiology"
DOI: 10.1007/s10571-017-0557-2
Abstract: In the heart, catecholamine effects occur by activation of beta-adrenergic receptors (β-ARs), mainly the beta 1 (β1-AR) and beta 2 (β2-AR) subtypes, both of which couple to the Gs protein that activates the adenylyl cyclase… read more here.
Keywords: stress; heart; beta adrenergic; heart failure ... See more keywords
Cell therapy rescues aging-induced beta-1 adrenergic receptor and GRK2 dysfunction in the coronary microcirculation.
Sign Up to like & getrecommendations! Published in 2021 at "GeroScience"
DOI: 10.1007/s11357-021-00455-6
Abstract: Our past study showed that coronary arterioles isolated from adipose-derived stromal vascular fraction (SVF)-treated rats showed amelioration of the age-related decrease in vasodilation to beta-adrenergic receptor (β-AR) agonist and improved β-AR-dependent coronary flow and microvascular… read more here.
Keywords: vasodilation; grk2; svf; receptor ... See more keywords
BETA ADRENERGIC RECEPTOR ACTIVATION INHIBITS ORAL CANCER MIGRATION AND INVASIVENESS.
Sign Up to like & getrecommendations! Published in 2020 at "Archives of oral biology"
DOI: 10.1016/j.archoralbio.2020.104865
Abstract: OBJECTIVE The aim of this study was to verify β2-AR expression in oral squamous cell carcinoma cell lines (SCC-9 and SCC-25), and to investigate the role of this receptor in migration and invasion of these… read more here.
Keywords: scc scc; migration; receptor; cell ... See more keywords
CD34+ hematopoietic stem cells are mobilized with exercise independently of beta-2 adrenergic receptor signaling
Sign Up to like & getrecommendations! Published in 2017 at "Brain, Behavior, and Immunity"
DOI: 10.1016/j.bbi.2017.07.087
Abstract: A single exercise bout mobilizes CD34+ hematopoietic stem cells (HSCs) to the bloodstream, potentially serving as an economical adjuvant to boost the collection of HSCs from stem cell transplant donors. The mechanisms responsible for HSC… read more here.
Keywords: stem; receptor signaling; receptor; adrenergic receptor ... See more keywords
The effect of beta-adrenergic blockade on inflammatory and cardiovascular responses to acute mental stress
Sign Up to like & getrecommendations! Published in 2018 at "Brain, Behavior, and Immunity"
DOI: 10.1016/j.bbi.2018.03.027
Abstract: Highlights • The mechanisms underlying acute stress-induced IL-6 responses are poorly understood.• We assessed the effects of beta-blockade with propranolol in a double-blind study.• Beta-blockade reduced IL-6 responses to stress in men but not women.•… read more here.
Keywords: adrenergic blockade; blockade inflammatory; beta; stress ... See more keywords
Protective effects of morphine in a rat model of post-traumatic stress disorder: Role of hypothalamic-pituitary-adrenal axis and beta- adrenergic system
Sign Up to like & getrecommendations! Published in 2020 at "Behavioural Brain Research"
DOI: 10.1016/j.bbr.2020.112867
Abstract: Post-traumatic stress disorder (PTSD) arises after tremendous traumatic experiences. Recently, we have reported that morphine has time-dependent protective effects against behavioral and morphological deficits in the single prolonged stress (SPS) as an experimental model of… read more here.
Keywords: beta adrenergic; stress; effects morphine; protective effects ... See more keywords
Autoantibodies with beta-adrenergic activity from chronic chagasic patients induce cardiac arrhythmias and early afterdepolarization in a drug-induced LQT2 rabbit hearts.
Sign Up to like & getrecommendations! Published in 2017 at "International journal of cardiology"
DOI: 10.1016/j.ijcard.2017.02.066
Abstract: BACKGROUND Cardiac arrhythmias are one of the main causes of death in ChCP and other dilated cardiomyopathies. Previous studies demonstrated that ventricular arrhythmias are associated with the presence of autoantibodies with beta-adrenergic activity, Ab-β. OBJECTIVES… read more here.
Keywords: autoantibodies beta; chronic chagasic; adrenergic activity; cardiac arrhythmias ... See more keywords
Beta adrenergic blockade and decompensated cirrhosis.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of hepatology"
DOI: 10.1016/j.jhep.2016.11.001
Abstract: Non-selective betablockers (NSBBs) remain the cornerstone of medical treatment of portal hypertension. The evidence for their efficacy to prevent variceal bleeding is derived from prospective trials, which largely excluded patients with refractory ascites and renal… read more here.
Keywords: adrenergic blockade; cirrhosis; blockade decompensated; decompensated cirrhosis ... See more keywords
Age-related neuroinflammation and pathology in the locus coeruleus and hippocampus: beta-adrenergic antagonists exacerbate impairment of learning and memory in aged mice
Sign Up to like & getrecommendations! Published in 2021 at "Neurobiology of Aging"
DOI: 10.1016/j.neurobiolaging.2021.06.012
Abstract: The locus coeruleus (LC) provides the primary noradrenergic input to the forebrain and hippocampus, and may be vulnerable to degeneration and contribute to age-related cognitive decline and neuroinflammation. Additionally, inhibition of noradrenergic transmission by brain-permeable… read more here.
Keywords: hippocampus; learning memory; pathology; aged mice ... See more keywords
Beta-adrenergic signaling promotes tumor angiogenesis and prostate cancer progression through HDAC2-mediated suppression of thrombospondin-1
Sign Up to like & getrecommendations! Published in 2017 at "Oncogene"
DOI: 10.1038/onc.2016.319
Abstract: Chronic behavioral stress and beta-adrenergic signaling have been shown to promote cancer progression, whose underlying mechanisms are largely unclear, especially the involvement of epigenetic regulation. Histone deacetylase-2 (HDAC2), an epigenetic regulator, is critical for stress-induced… read more here.
Keywords: adrenergic signaling; beta adrenergic; cancer progression;