Electronic health record (EHR) based postmarketing surveillance of adverse events associated with pediatric off‐label medication use: A case study of short‐acting beta‐2 agonists and arrhythmias
Sign Up to like & getrecommendations! Published in 2018 at "Pharmacoepidemiology and Drug Safety"
DOI: 10.1002/pds.4562
Abstract: Use electronic health record (EHR) data to (1) estimate the risk of arrhythmia associated with inhaled short‐acting beta‐2 agonists (SABA) in pediatric patients and (2) determine whether risk varied by on‐label versus off‐label prescribing. read more here.
Keywords: acting beta; beta agonists; short acting; electronic health ... See more keywords
LBMON186 Beta-agonist Profiling Reveals Novel Biased Signaling Phenotypes For The Beta 2-adrenergic Receptor With Implications In The Treatment Of Asthma
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DOI: 10.1210/jendso/bvac150.1217
Abstract: Asthma is characterized by chronic airway inflammation and airway smooth muscle (ASM) cell contraction. Current treatments for asthma include beta‐agonists which activate the beta 2‐adrenergic receptor, a G protein‐coupled receptor (GPCR) that promotes Gs‐dependent production… read more here.
Keywords: beta agonists; beta; beta arrestin; adrenergic receptor ... See more keywords