Effect of beta‐blockade on mortality in patients with cardiac amyloidosis: A systematic review and meta‐analysis
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DOI: 10.1002/ehf2.14975
Abstract: The efficacy of beta‐blockers in cardiac amyloidosis (CA) is unclear, and concerns persist that neurohormonal blockade could worsen symptoms of heart failure. We aimed to assess whether beta‐blocker therapy is associated with improved survival in… read more here.
Keywords: cardiac amyloidosis; beta blockade; beta; effect beta ... See more keywords
Beta blockade in TBI: Dose-dependent reductions in BBB leukocyte mobilization and permeability in vivo
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Trauma and Acute Care Surgery"
DOI: 10.1097/ta.0000000000003537
Abstract: Beta blockade in severe traumatic brain injury has shown improvements in survival and recovery after injury. This paper demonstrates in a series of in vivo and ex vivo experiments a potential mechanism for this benefit… read more here.
Keywords: dose dependent; tbi; beta blockade; permeability ... See more keywords
Nonselective beta blockade enhances gut microbiome diversity in a rodent model of trauma, hemorrhage, and chronic stress
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Trauma and Acute Care Surgery"
DOI: 10.1097/ta.0000000000004461
Abstract: BACKGROUND Traumatic injury leads to gut dysbiosis with changes in microbiome diversity and conversion toward a “pathobiome” signature characterized by a selective overabundance of pathogenic bacteria. The use of non-selective beta antagonism in trauma patients… read more here.
Keywords: beta blockade; gut microbiome; beta; microbiome diversity ... See more keywords
Beta-blockade enhances anthracycline control of metastasis in triple-negative breast cancer
Sign Up to like & getrecommendations! Published in 2023 at "Science Translational Medicine"
DOI: 10.1126/scitranslmed.adf1147
Abstract: Beta-adrenergic blockade has been associated with improved cancer survival in patients with triple-negative breast cancer (TNBC), but the mechanisms of these effects remain unclear. In clinical epidemiological analyses, we identified a relationship between beta-blocker use… read more here.
Keywords: anthracycline chemotherapy; beta blockade; breast cancer; beta ... See more keywords
To block, or not to block … is it still the question? Effectiveness of alpha- and beta-blockade in phaeochromocytoma surgery: an institutional analysis.
Sign Up to like & getrecommendations! Published in 2022 at "Annals of the Royal College of Surgeons of England"
DOI: 10.1308/rcsann.2021.1077
Abstract: INTRODUCTION Phaeochromocytomas/paraganglioma (PPGL) surgery was historically associated with significant risks of perioperative complications. The decreased mortality (160mmHg, SBP 160mmHg. Nine (17%) cases had no intraoperative hypotensive episodes, while 3 (6%) patients had >10 intraoperative episodes… read more here.
Keywords: alpha beta; block; surgery; beta blockade ... See more keywords