Key Role of Disulfide Bridges in the Antimicrobial Activity of Beta-Defensin from Olive Flounder
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Peptide Research and Therapeutics"
DOI: 10.1007/s10989-019-09837-z
Abstract: Proteins that contain multiple disulfide bonds (SS bonds) expressed in Escherichia coli are usually problematic. This study reports the successful recombinant expression of the antimicrobial peptide β-defensin isolated from olive flounder in E. coli .… read more here.
Keywords: defensin; olive flounder; beta defensin; spectroscopy ... See more keywords
Association of systemic beta-defensin-1 and -20G/A DEFB1 gene polymorphism with Behçet's disease.
Sign Up to like & getrecommendations! Published in 2019 at "European journal of internal medicine"
DOI: 10.1016/j.ejim.2019.02.008
Abstract: BACKGROUND Behçet's disease (BD) is a multisystem inflammatory disease of unknown etiology. Beta-defensins are antimicrobial peptides involved in epithelial host defense. To explore whether beta-defensins might be involved in BD pathogenesis, we examined plasma human… read more here.
Keywords: beta defensin; disease; beta; beh disease ... See more keywords
Haplotype structure and copy number polymorphism of the beta-defensin 7 genes in diverse chicken breeds.
Sign Up to like & getrecommendations! Published in 2017 at "Animal genetics"
DOI: 10.1111/age.12552
Abstract: Beta-defensins is a family of avian peptides related to the innate immune system. Copy number variation was recently reported for the avian beta-defensin 7 gene (AvBD7) between the highly inbred Leghorn and Fayoumi lines. Here,… read more here.
Keywords: beta defensin; copy number; chicken breeds; beta ... See more keywords
Association of human beta‐defensin 1 gene polymorphisms with nonsegmental vitiligo
Sign Up to like & getrecommendations! Published in 2019 at "Clinical and Experimental Dermatology"
DOI: 10.1111/ced.13697
Abstract: Vitiligo is a pigmentation disorder of autoimmune aetiology. Polymorphisms in beta‐defensin genes have been linked to a predisposition to some autoimmune disorders. read more here.
Keywords: defensin; beta defensin; gene polymorphisms; defensin gene ... See more keywords
Gingival Tissue Human Beta-Defensin Levels in Relation to Infection and Inflammation.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of clinical periodontology"
DOI: 10.1111/jcpe.13227
Abstract: AIM To profile gingival tissue levels of human beta-defensin (hBD)-2 and hBD-3 in relation to gingival inflammation, Th17-related cytokine concentrations, Porphyromonas gingivalis counts, and gingipain and total protease activities. MATERIALS AND METHODS Gingival tissue and… read more here.
Keywords: gingival tissue; beta defensin; hbd; inflammation ... See more keywords
Human Beta Defensin 2 Ameliorated Alcohol-Associated Liver Disease in Mice
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2021.812882
Abstract: Alcohol-associated liver disease (ALD) is a prevalent liver disorder and significant global healthcare burden with limited effective therapeutic options. The gut-liver axis is a critical factor contributing to susceptibility to liver injury due to alcohol… read more here.
Keywords: alcohol associated; beta defensin; liver disease; associated liver ... See more keywords
Andrographolide and 4-Phenylbutyric Acid Administration Increase the Expression of Antimicrobial Peptides Beta-Defensin-1 and Cathelicidin and Reduce Mortality in Murine Sepsis
Sign Up to like & getrecommendations! Published in 2022 at "Antibiotics"
DOI: 10.3390/antibiotics11111629
Abstract: Antibiotic resistance is a global threat and requires the search for new treatment strategies. Natural antimicrobial peptides (AMPs) have pronounced antibacterial, antiviral, antifungal, and antitumor activity. AMPs’ clinical use is complicated by the high synthesis… read more here.
Keywords: mortality murine; antimicrobial peptides; beta defensin; expression ... See more keywords
In silico docking analysis of beta-defensin 20 against cation channel sperm-associated protein 1-4 to predict its role in the sperm maturation.
Sign Up to like & getrecommendations! Published in 2022 at "Asian journal of andrology"
DOI: 10.4103/aja2022103
Abstract: Beta-defensin 20 (DEFB20) is widely expressed in the epididymis with gene features involved in epididymal sperm maturation. However, the action mechanism and function of DEFB20 in sperm maturation are still unclear. One of the important… read more here.
Keywords: sperm maturation; channel; beta defensin;
[Investigation of cytokine responses and variations in the expression of beta-defensin-3 of Caco-2 human colon epidermal adenocarsinoma and THP-1 human leukemia monocyte cell lines in response to Toxoplasma gondii under various conditions].
Sign Up to like & getrecommendations! Published in 2017 at "Mikrobiyoloji bulteni"
DOI: 10.5578/mb.53941
Abstract: Mononuclear phogocytic cells and epithelial cells are effective during the initiation and regulation of the innate immune response. They have an active role in mucosal immune response both mechanically and by interaction with other cells… read more here.
Keywords: response; beta defensin; human colon; thp human ... See more keywords