Articles with "beta glycoprotein" as a keyword



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Anticardiolipin and anti‐beta 2‐glycoprotein I antibodies in patients with unexplained articular manifestations

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Published in 2022 at "Journal of Clinical Laboratory Analysis"

DOI: 10.1002/jcla.24812

Abstract: To determine the frequency of antiphospholipid antibodies (aPL) in patients with unexplained articular manifestations. read more here.

Keywords: articular manifestations; unexplained articular; anticardiolipin anti; patients unexplained ... See more keywords
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Cross-reactivity between annexin A2 and Beta-2-glycoprotein I in animal models of antiphospholipid syndrome

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Published in 2017 at "Immunologic Research"

DOI: 10.1007/s12026-016-8840-8

Abstract: Antiphospholipid syndrome (APS) affects coagulation and the brain by autoimmune mechanisms. The major antigen in APS is beta-2-glycoprotein I (β2-GPI) is known to complex with annexin A2 (ANXA2), and antibodies to ANXA2 have been described… read more here.

Keywords: antiphospholipid syndrome; anxa2 antibodies; annexin; beta glycoprotein ... See more keywords
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Anti-beta 2 glycoprotein I IgA in the SLICC classification criteria dataset

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Published in 2021 at "Lupus"

DOI: 10.1177/09612033211014248

Abstract: Objective Anti-beta 2 glycoprotein I IgA is a common isotype of anti-beta 2 glycoprotein I in SLE. Anti-beta 2 glycoprotein I was not included in the American College of Rheumatology (ACR) SLE classification criteria, but… read more here.

Keywords: anti beta; glycoprotein iga; beta glycoprotein;
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A systematic review of the association between anti-beta-2 glycoprotein I antibodies and APS manifestations.

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Published in 2021 at "Blood advances"

DOI: 10.1182/bloodadvances.2021005205

Abstract: Anti-beta-2 glycoprotein I antibodies (anti-B2GPI) are often cited as the major pathogenically relevant antibody in antiphospholipid syndrome (APS), but it is unclear if there is clinical evidence to support this theory. We performed a systematic… read more here.

Keywords: systematic review; beta glycoprotein; association; anti b2gpi ... See more keywords
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Beta-2-glycoprotein I as a biomarker for sepsis in critically ill patients in the intensive care unit: a prospective cohort study

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Published in 2020 at "Critical Care"

DOI: 10.1186/s13054-020-03066-3

Abstract: No abstract available Keywords: Apolipoprotein H; B2GPI; Biomarkers; Critical care; ICU; SIRS; Sepsis. read more here.

Keywords: sepsis; sepsis critically; biomarker sepsis; beta glycoprotein ... See more keywords
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Antiphospholipid Antibodies to Domain I of Beta-2-Glycoprotein I Show Different Subclass Predominance in Comparison to Antibodies to Whole Beta-2-glycoprotein I

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Published in 2018 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2018.02244

Abstract: Antiphospholipid antibodies (aPL), the serological hallmark of antiphospholipid syndrome (APS), are a heterogeneous group of autoantibodies raised against circulating blood proteins. Of these proteins, the phospholipid-binding b2-glycoprotein I (β2GPI) is considered to be the main… read more here.

Keywords: igg; adi; beta glycoprotein; subclass ... See more keywords
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PEGylated Domain I of Beta-2-Glycoprotein I Inhibits the Binding, Coagulopathic, and Thrombogenic Properties of IgG From Patients With the Antiphospholipid Syndrome

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Published in 2018 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2018.02413

Abstract: APS is an autoimmune disease in which antiphospholipid antibodies (aPL) cause vascular thrombosis and pregnancy morbidity. In patients with APS, aPL exert pathogenic actions by binding serum beta-2-glycoprotein I (β2GPI) via its N-terminal domain I… read more here.

Keywords: pegylated domain; domain beta; beta glycoprotein; beta ... See more keywords
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PEGylated Domain I of Beta-2-Glycoprotein I Inhibits Thrombosis in a Chronic Mouse Model of the Antiphospholipid Syndrome

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Published in 2022 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2022.842923

Abstract: Antiphospholipid syndrome (APS) is an autoimmune disorder in which autoantibodies cause clinical effects of vascular thrombosis and pregnancy morbidity. The only evidence-based treatments are anticoagulant medications such as warfarin and heparin. These medications have a… read more here.

Keywords: beta glycoprotein; thrombosis; mouse model; model ... See more keywords