Aspartate beta-hydroxylase promotes cholangiocarcinoma progression by modulating RB1 phosphorylation.
Sign Up to like & getrecommendations! Published in 2018 at "Cancer letters"
DOI: 10.1016/j.canlet.2018.04.041
Abstract: Cholangiocarcinoma (CCA) is a highly lethal and aggressive disease. Recently, IDH1/2 mutations have been identified in approximately 20% of CCAs which suggests an involvement of 2-oxoglutarate (2-OG) -dependent dioxygenases in oncogenesis. We investigated if the… read more here.
Keywords: aspartate beta; rb1 phosphorylation; modulating rb1; progression ... See more keywords
Dopamine beta‐hydroxylase and its genetic variants in human health and disease
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DOI: 10.1111/jnc.14893
Abstract: Dopamine beta‐hydroxylase (DβH) is an essential neurotransmitter‐synthesizing enzyme that catalyzes the formation of norepinephrine (NE) from dopamine and has been extensively studied since its discovery in the 1950s. NE serves as a neurotransmitter in both… read more here.
Keywords: dopamine beta; genetic variants; dopamine; disease ... See more keywords
Pregnancy in a woman with congenital adrenal hyperplasia with 11-beta-hydroxylase deficiency: A case report
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DOI: 10.1177/1753495x211042729
Abstract: Successful pregnancy with congenital adrenal hyperplasia due to 11-beta-hydroxylase deficiency is an extremely rare condition. Only two cases have been reported in the literature. Described here is a 30-year-old woman diagnosed as a neonate with… read more here.
Keywords: pregnancy; hydroxylase deficiency; adrenal hyperplasia; congenital adrenal ... See more keywords