Abstract A08: PI3Kbeta regulates beta-1 integrin signaling in invadopodia through formation of PI(3,4)P2
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DOI: 10.1158/1557-3125.pi3k-mtor18-a08
Abstract: The PI3Kbeta isoform of PI 3-kinase, which is activated downstream from both RTKs and GPCRs, is an important regulator of invadopodia formation. We have previously reported that in MDA-MB-231 breast cancer cells, replacement of endogenous… read more here.
Keywords: pi3kbeta; invadopodia formation; beta integrin; integrin signaling ... See more keywords