Beta-lactams in continuous infusion for Gram-negative bacilli osteoarticular infections: an easy method for clinical use
Sign Up to like & getrecommendations! Published in 2018 at "Infection"
DOI: 10.1007/s15010-018-1116-6
Abstract: Continuous infusion (CI) of beta-lactams could optimize their pharmacokinetic/pharmacodynamic indices, especially in difficult-to-treat infections.PurposeTo validate an easy-to-use method to guide beta-lactams dosage in CI (formula).MethodsA retrospective analysis was conducted of a prospectively collected cohort (n = 24… read more here.
Keywords: continuous infusion; use; osteoarticular infections; gram negative ... See more keywords
Development and validation of an enzyme-linked receptor assay based on mutant protein I188K/S19C/G24C for 40 beta-lactams antibiotics detection in 13 food samples
Sign Up to like & getrecommendations! Published in 2020 at "Microchemical Journal"
DOI: 10.1016/j.microc.2019.104354
Abstract: Abstract Antibiotics play an important role in disease prevention and as a growth promoter in the veterinary field. Animals derived foods holding antibiotic residues above the maximum residue limits can contribute as a hazardous effect… read more here.
Keywords: s19c g24c; beta lactams; beta; protein i188k ... See more keywords
Jumping into the future: overcoming pharmacokinetic/pharmacodynamic hurdles to optimize the treatment of severe difficult to treat-Gram-negative infections with novel beta-lactams
Sign Up to like & getrecommendations! Published in 2023 at "Expert Review of Anti-infective Therapy"
DOI: 10.1080/14787210.2023.2169131
Abstract: ABSTRACT Introduction The choice of best therapeutic strategy for difficult-to-treat resistance (DTR) Gram-negative infections currently represents an unmet clinical need. Areas covered This review provides a critical reappraisal of real-world evidence supporting the role of… read more here.
Keywords: dtr gram; difficult treat; novel beta; negative infections ... See more keywords
Validation of the AnticFast® Beta-Lactams Rapid Test Kit for Detection of Beta-Lactams (Penicillins and Cephalosporins) in Raw Cow's Milk: AOAC Performance Tested MethodSM 032303.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of AOAC International"
DOI: 10.1093/jaoacint/qsad054
Abstract: BACKGROUND AnticFast® Beta-lactams Rapid Test Kit is a qualitative two-step (2 min + 5 min) rapid lateral flow assay to detect β-lactam (penicillins and cephalosporins) antibiotic residues in raw commingled cow's milk. OBJECTIVE The method performance was… read more here.
Keywords: detection; beta lactams; test kit; milk ... See more keywords
Clinical Outcomes With Extended Versus Intermittent Infusion of Anti-Pseudomonal Beta-Lactams in Patients With Gram-Negative Bacteremia
Sign Up to like & getrecommendations! Published in 2023 at "Open Forum Infectious Diseases"
DOI: 10.1093/ofid/ofad170
Abstract: Abstract Background Administration of doses via an extended infusion (EI) is an important strategy to optimize beta-lactams. Available data on the impact of EI on outcomes largely focus on clinical cure or mortality in critically… read more here.
Keywords: bacteremia; infusion; beta lactams; gram negative ... See more keywords
Non‐immediate‐reading skin tests and prolonged challenges in non‐immediate hypersensitivity to beta‐lactams in children
Sign Up to like & getrecommendations! Published in 2018 at "Pediatric Allergy and Immunology"
DOI: 10.1111/pai.12826
Abstract: A minority of children reporting non‐immediate reactions to beta‐lactams (BLs) are allergic. Allergy workup usually includes late‐reading (48‐72 hours) skin tests (ST) and short (1‐3 days) drug provocation tests (DPT), regardless of the chronology of… read more here.
Keywords: non immediate; skin tests; beta lactams; immediate hypersensitivity ... See more keywords
An EAACI Task Force report on allergy to beta‐lactams in children: Clinical entities and diagnostic procedures
Sign Up to like & getrecommendations! Published in 2021 at "Pediatric Allergy and Immunology"
DOI: 10.1111/pai.13529
Abstract: Beta‐lactam (BL) allergy suspicion is common in children and constitutes a major public health problem, with an impact on patient's health and on medical costs. However, it has been found that most of these reactions… read more here.
Keywords: allergy beta; eaaci task; report allergy; beta lactams ... See more keywords
Uncovering Beta-Lactam Susceptibility Patterns in Clinical Isolates of Mycobacterium tuberculosis through Whole-Genome Sequencing
Sign Up to like & getrecommendations! Published in 2022 at "Microbiology Spectrum"
DOI: 10.1128/spectrum.00674-22
Abstract: Associations between differential M. tuberculosis beta-lactam phenotypes and preexisting antimycobacterial drug resistance, strain sublineage, or specific mutational patterns were established. Importantly, we reveal that highly drug-resistant isolates of sublineage 4.3.4.2 have an increased susceptibility to… read more here.
Keywords: beta lactam; beta; tuberculosis; susceptibility ... See more keywords
Perioperative Anaphylaxis Including Kounis Syndrome due to Selective Cefazolin Allergy
Sign Up to like & getrecommendations! Published in 2018 at "International Archives of Allergy and Immunology"
DOI: 10.1159/000490182
Abstract: Background: Perioperative use of cefazolin has been associated with severe allergic reactions, and patients are usually labelled as allergic to penicillin afterwards. The aim of our study was to describe a group of patients with… read more here.
Keywords: perioperative anaphylaxis; beta lactams; anaphylaxis including; allergy ... See more keywords
Infection-stage adjusted dose of beta-lactams for parsimonious and efficient antibiotic treatments: A Pasteurella multocida experimental pneumonia in mice
Sign Up to like & getrecommendations! Published in 2017 at "PLoS ONE"
DOI: 10.1371/journal.pone.0182863
Abstract: In this study, the impact of infection stage on clinically and microbiologically efficacious doses and on antibiotic consumption was assessed during a naturally evolving infectious disease, using an original mouse model of pulmonary infection produced… read more here.
Keywords: infection stage; infection; pasteurella multocida; beta lactams ... See more keywords
Comparison of Clinical Outcomes for Glycopeptides and Beta-Lactams in Methicillin-Susceptible Staphylococcus Aureus Bloodstream Infections
Sign Up to like & getrecommendations! Published in 2022 at "Yonsei Medical Journal"
DOI: 10.3349/ymj.2022.63.7.611
Abstract: Purpose This study aimed to provide compelling evidence of anti-staphylococcal beta-lactam use for methicillin-susceptible Staphylococcus aureus bloodstream infection (MSSA BSI). Materials and Methods We retrospectively collected data on patients with MSSA BSI who were admitted… read more here.
Keywords: aureus bloodstream; methicillin susceptible; staphylococcus aureus; definitive therapy ... See more keywords