Expression analysis of beta-secretase 1 (BACE1) and its naturally occurring antisense (BACE1-AS) in blood of epileptic patients
Sign Up to like & getrecommendations! Published in 2018 at "Neurological Sciences"
DOI: 10.1007/s10072-018-3458-3
Abstract: Beta-secretase 1 (BACE1) gene encodes a transmembrane protease from the peptidase A1 family of aspartic proteases whose role in the pathogenesis of Alzheimer’s disease has been assessed. The enzymatic activity of BACE1 on several proteins… read more here.
Keywords: secretase bace1; bace1 naturally; expression; naturally occurring ... See more keywords
Computational studies on the cholinesterase, beta-secretase 1 (BACE1) and monoamine oxidase (MAO) inhibitory activities of endophytes-derived compounds: towards discovery of novel neurotherapeutics
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Biomolecular Structure and Dynamics"
DOI: 10.1080/07391102.2022.2035255
Abstract: Abstract Cholinesterases, beta-secretase 1 (BACE1) and monoamine oxidase (MAO) are significant in the etiology of neurodegenerative diseases. Inhibition of these enzymes is therefore a major strategy for the development of neurotherapeutics. Even though, this strategy… read more here.
Keywords: secretase bace1; endophytes derived; bace1 monoamine; derived compounds ... See more keywords
Expression analysis of beta-secretase 1 (BACE1) enzyme in peripheral blood of patients with Alzheimer's disease
Sign Up to like & getrecommendations! Published in 2019 at "Caspian Journal of Internal Medicine"
DOI: 10.22088/cjim.10.3.276
Abstract: Background: Recent evidence has indicated that beta-secretase 1 (BACE1) is involved in the production of amyloid beta (Aβ) in patients affected with Alzheimer’s disease (AD). Therefore; the purpose of this study was to measure mRNA… read more here.
Keywords: secretase bace1; alzheimer disease; blood; expression ... See more keywords
Contrasting effects of acute and long-term corticosterone treatment on amyloid-β, beta-secretase 1 expression, and nuclear factor kappa B nuclear translocation.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of integrative neuroscience"
DOI: 10.31083/j.jin.2019.04.1172
Abstract: Regulation of neuroinflammation is critical to control the detrimental impact of chronic stress in the central nervous system. Neuroinflammation occurs in response to chronic stress, leading to enhanced neuronal damage in the brain. We investigated… read more here.
Keywords: beta secretase; neuroinflammation; corticosterone; neuroinflammation regulator ... See more keywords