Beta-Sitosterol-Conjugated Sinapic Acid-Engineered Nanoliposome: Biomucoadhesive and Enzyme-Responsive Targeted Oral Therapy in Ulcerative Colitis.
Sign Up to like & getrecommendations! Published in 2025 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.5c02190
Abstract: Developing oral drug delivery systems is promising for ulcerative colitis (UC). However, the key challenges, including formulation degradation under harsh gastric conditions, poor targeting efficiency, and limited colonic residence, lead to poor therapeutic efficacy that… read more here.
Keywords: enzyme responsive; ulcerative colitis; beta sitosterol; sinapic acid ... See more keywords
Beta-sitosterol alleviates inflammatory culprits and disease severity in arthritic irradiated rat's model: Role of brain-spleen axis.
Sign Up to like & getrecommendations! Published in 2025 at "Immunopharmacology and immunotoxicology"
DOI: 10.1080/08923973.2025.2591423
Abstract: BackgroundThe complex interaction between the adaptive immune system and innate immunological components causes rheumatoid arthritis (RA), a systemic autoimmune disorder that involves synovitis and joint deformity. Brain- spleen axis is a reciprocal cross-communicative circuit serves… read more here.
Keywords: brain; spleen axis; arthritic irradiated; brain spleen ... See more keywords
Transcriptomic analysis reveals the inhibitory effect of beta-sitosterol on proliferation of bovine preadipocytes
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DOI: 10.1080/10495398.2024.2339406
Abstract: Abstract Fat deposition affects beef quantity and quality via preadipocyte proliferation. Beta-sitosterol, a natural small molecular compound, has various functions, such as anti-inflammation, antibacterial, and anticancer properties. The mechanism of action of Beta-sitosterol on bovine… read more here.
Keywords: proliferation bovine; sitosterol; beta sitosterol; bovine preadipocytes ... See more keywords
Pyrus communis L. (Pear) and Malus domestica Borkh. (apple) leaves lipoidal extracts as sources for beta-sitosterol rich formulae and their wound healing evaluation.
Sign Up to like & getrecommendations! Published in 2022 at "Natural product research"
DOI: 10.1080/14786419.2022.2056181
Abstract: Pyrus communis L. (cv. Le-Conte) (pears) and Malus domestica Borkh. (cv. Anna) (apples) are economic fruit crops cultivated in Egypt. Their leaves were assessed for their beta-sitosterol content and found to have 9.4 mg/g dried leaves… read more here.
Keywords: wound healing; pyrus communis; domestica borkh; beta sitosterol ... See more keywords
Beta-sitosterol upregulated paraoxonase-1 via peroxisome proliferator-activated receptor-γ in irradiated rats.
Sign Up to like & getrecommendations! Published in 2017 at "Canadian journal of physiology and pharmacology"
DOI: 10.1139/cjpp-2016-0397
Abstract: This study was designed to evaluate the effect of beta-sitosterol (BS) on the peroxisome proliferator-activated receptor gamma (PPAR-γ) gene expression role in the activity of paraoxonase (PON-1) enzyme in oxidative stress status of irradiated rats.… read more here.
Keywords: peroxisome proliferator; proliferator activated; cholesterol; activated receptor ... See more keywords
Network Pharmacology‐Based Experimental Validation on the Mechanism of Cang’erzi Powder in Treating Asthma
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DOI: 10.1155/ijcp/6511743
Abstract: Background: Cang’erzi powder, a medicinal formula, has had an extensive application in the treatment of asthma in China. Network pharmacological methods and experimental validation were used to investigate the underlying mechanism of Cang’erzi powder in… read more here.
Keywords: cang erzi; erzi powder; beta sitosterol; pharmacology ... See more keywords