The impact of amyloid‐beta and tau on prospective cognitive decline in older individuals
Sign Up to like & getrecommendations! Published in 2019 at "Annals of Neurology"
DOI: 10.1002/ana.25395
Abstract: Amyloid‐beta (Aβ) and tau pathologies are commonly observed among clinically normal older individuals at postmortem and can now be detected with in vivo neuroimaging. The association and interaction of these proteinopathies with prospective cognitive decline… read more here.
Keywords: prospective cognitive; amyloid beta; beta tau; older individuals ... See more keywords
Near-Infrared Fluorescent Probes as Imaging and Theranostic Modalities for Amyloid-Beta and Tau Aggregates in Alzheimer's Disease.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of medicinal chemistry"
DOI: 10.1021/acs.jmedchem.1c01619
Abstract: A person suspected of having Alzheimer's disease (AD) is clinically diagnosed for the presence of principal biomarkers, especially misfolded amyloid-beta (Aβ) and tau proteins in the brain regions. Existing radiotracer diagnostic tools, such as PET… read more here.
Keywords: alzheimer disease; amyloid beta; near infrared; beta tau ... See more keywords
Modeling amyloid beta and tau pathology in human cerebral organoids
Sign Up to like & getrecommendations! Published in 2018 at "Molecular Psychiatry"
DOI: 10.1038/s41380-018-0229-8
Abstract: The typical abnormalities observed in the brain of Alzheimer’s disease (AD) patients include synaptic alterations, neuronal death, brain inflammation, and the accumulation of protein aggregates in the form of amyloid plaques and neurofibrillary tangles. Despite… read more here.
Keywords: amyloid beta; pathology; beta tau; cerebral organoids ... See more keywords
0564 The mechanism of deficits in cognition of OSA: plasma amyloid-beta and tau protein level by the intervention design
Sign Up to like & getrecommendations! Published in 2023 at "SLEEP"
DOI: 10.1093/sleep/zsad077.0564
Abstract: Obstructive sleep apnea syndrome (OSAS) was shown to impair neurocognitive functioning, which was often attributed to hypoxia and sleep fragmentation. More recently, increased accumulation of amyloid-beta and tau protein in OSAS patients have gotten research… read more here.
Keywords: tau protein; amyloid beta; tau; beta tau ... See more keywords
Amyloid-beta peptide and tau protein crosstalk in Alzheimer’s disease
Sign Up to like & getrecommendations! Published in 2022 at "Neural Regeneration Research"
DOI: 10.4103/1673-5374.332127
Abstract: Alzheimer’s disease is a neurodegenerative disease that accounts for most of the 50-million dementia cases worldwide in 2018. A large amount of evidence supports the amyloid cascade hypothesis, which states that amyloid-beta accumulation triggers tau… read more here.
Keywords: alzheimer disease; amyloid beta; beta tau; beta ... See more keywords