Microwave assisted synthesis of fluorescent hetero atom doped carbon dots for determination of betrixaban with greenness evaluation
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DOI: 10.1039/d3ra00824j
Abstract: A simple, rapid and eco-friendly method for synthesis of nitrogen and sulfur doped carbon dots (N,S-CDs) is described. The method involved one step carbonization assisted by a green microwave irradiation route using available and cheap… read more here.
Keywords: betrixaban; synthesis; determination; doped carbon ... See more keywords
The benefit of betrixaban for the extended thromboprophylaxis in acutely ill medical patients
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DOI: 10.1080/14656566.2018.1558209
Abstract: ABSTRACT Introduction: Patients admitted with acute medical conditions are at prolonged risk for venous thrombosis. The efficacy and safety, and the appropriate duration of thromboprophylaxis have not been clearly determined. In recent years, direct coagulation… read more here.
Keywords: acutely ill; ill medical; extended thromboprophylaxis; thromboprophylaxis acutely ... See more keywords
Optimization and Validation of a Facile RP-HPLC Method for Determination of Betrixaban and Lercanidipine in Pharmaceutical and Biological Matrices.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of chromatographic science"
DOI: 10.1093/chromsci/bmab088
Abstract: A simple, accurate, rapid and sensitive reversed-phase high-performance liquid chromatography (RP-HPLC) method was established for determination of a novel non-vitamin K antagonist oral anticoagulant drug, betrixaban, and its co-administered calcium-channel blocker drug, lercanidipine, in pharmaceutical… read more here.
Keywords: determination; method; betrixaban lercanidipine; hplc method ... See more keywords
Development of three ecological spectroscopic methods for analysis of betrixaban either alone or in mixture with lercanidipine: greenness assessment
Sign Up to like & getrecommendations! Published in 2022 at "Royal Society Open Science"
DOI: 10.1098/rsos.211457
Abstract: Three eco-friendly spectrophotometric methods were developed for determination of the novel anticoagulant drug, betrixaban (BTX). The first method (method A) was based on direct analysis of BTX at 229.4 nm on the zero-order spectrum using… read more here.
Keywords: analysis; betrixaban; greenness; method ... See more keywords
Net‐clinical benefit of extended prophylaxis of venous thromboembolism with betrixaban in medically ill patients aged 80 or more
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Thrombosis and Haemostasis"
DOI: 10.1111/jth.14600
Abstract: Extended‐duration thromboprophylaxis with betrixaban reduces the risk of venous thromboembolism (VTE) without increasing major bleeding rates in acutely ill medical patients as compared to standard duration enoxaparin. We aimed to assess the risk‐benefit of betrixaban… read more here.
Keywords: benefit; net clinical; venous thromboembolism; patients aged ... See more keywords