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Published in 2017 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2017.35.15_suppl.e14065
Abstract: Background: BEVZ92 has being developed as a proposed biosimilar approved reference medicine product (RMP). BEVZ92 has an identical amino acid sequence and highly similar physicochemical and in vitro functional properties to RMP. The aim of…
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Keywords:
compared rmp;
treatment;
results bevacizumab;
biosimilar compared ... See more keywords
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Published in 2025 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2025.1594935
Abstract: Background Programmed cell death-1/programmed cell death-ligand 1 (PD-[L]1) inhibitors plus bevacizumab (or biosimilars) or tyrosine kinase inhibitors (TKIs) have been widely used for the first-line treatment of patients with unresectable hepatocellular carcinoma (uHCC). However, no…
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Keywords:
treatment;
tislelizumab plus;
plus lenvatinib;
sintilimab plus ... See more keywords
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Published in 2023 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.1036906
Abstract: Background Bevacizumab has played an important role in the systemic treatment of patients with advanced non-small-cell lung cancer (NSCLC) without gene mutation. In recent years, bevacizumab biosimilar has received marketing approval based on the results…
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Keywords:
locally advanced;
reference;
bevacizumab;
efficacy safety ... See more keywords
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Published in 2025 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2025.1681663
Abstract: Background Sintilimab plus a Bevacizumab biosimilar (IBI305) is an approved first-line regimen for unresectable hepatocellular carcinoma (uHCC) in China. However, data on its safety and efficacy in patients with impaired liver function remain limited. We…
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Keywords:
biosimilar ibi305;
function;
liver function;
sintilimab plus ... See more keywords
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Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.778505
Abstract: Objective: The ORIENT-32 clinical trial revealed that sintilimab plus bevacizumab biosimilar significantly improved the median progression-free survival and median overall survival (OS) compared with sorafenib. This analysis evaluated the cost-effectiveness of sintilimab plus bevacizumab biosimilar…
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Keywords:
plus bevacizumab;
first line;
sintilimab plus;
cost effectiveness ... See more keywords