Effects of selective serotonin‐reuptake inhibitors (SSRIs) on human villous trophoblasts syncytialization
Sign Up to like & getrecommendations! Published in 2018 at "Toxicology and Applied Pharmacology"
DOI: 10.1016/j.taap.2018.04.018
Abstract: ABSTRACT Selective serotonin‐reuptake inhibitors (SSRIs) are the most commonly prescribed antidepressants during pregnancy. The human placenta is a highly specialized organ supporting normal growth and development of the fetus. Therefore, this study aims to analyze… read more here.
Keywords: selective serotonin; villous trophoblasts; trophoblast; syncytialization ... See more keywords
Integrin linked kinase regulates syncytialization of BeWo trophoblast cells†
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DOI: 10.1095/biolreprod.116.145748
Abstract: Abstract During placental development, mononuclear villous cytotrophoblast cells differentiate and fuse with the overlying syncytiotrophoblast. This process requires the dissolution of E-cadherin (CDH1)-containing adherens junctions in cytotrophoblast. Integrin linked kinase (ILK) can downregulate CDH1 through… read more here.
Keywords: parp1 snai1; syncytialization; bewo; ilk ... See more keywords
The impact of hyperglycemia upon BeWo trophoblast cell metabolic function: A multi-OMICS and functional metabolic analysis
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DOI: 10.1371/journal.pone.0283118
Abstract: Pre-existing and gestationally-developed diabetes mellitus have been linked with impaired metabolic function in placental villous trophoblast cells, that is thought to underlie the development of metabolic diseases early in the lives of the exposed offspring.… read more here.
Keywords: function; metabolic function; multi omics; bewo ... See more keywords