Versican silencing in BeWo cells and its implication in gestational trophoblastic diseases
Sign Up to like & getrecommendations! Published in 2018 at "Histochemistry and Cell Biology"
DOI: 10.1007/s00418-018-1739-9
Abstract: Versican is a proteoglycan known to interact with cells to influence their ability to proliferate, differentiate, migrate, invade and assemble extracellular matrix, with all of these cell functions present during placentation. In the placenta, cytotrophoblast… read more here.
Keywords: trophoblastic diseases; silencing bewo; bewo cells; gestational trophoblastic ... See more keywords
Tumor necrosis factor-α regulates angiogenesis of BeWo cells via synergy of PlGF/VEGFR1 and VEGF-A/VEGFR2 axes.
Sign Up to like & getrecommendations! Published in 2018 at "Placenta"
DOI: 10.1016/j.placenta.2018.12.009
Abstract: OBJECTIVES Tumor necrosis factor-alpha (TNF- α) promotes tumor growth by enhancing tumor angiogenesis; however, the effects on choriocarcinoma remain unknown. We investigated the effects of TNF-α on the production of placental growth factor (PlGF) and… read more here.
Keywords: vegf; plgf; bewo cells; vegfr1 ... See more keywords
miR‐27b‐5p inhibits BeWo cells fusion by regulating WNT2B and enzyme involved in progesterone synthesis
Sign Up to like & getrecommendations! Published in 2021 at "American Journal of Reproductive Immunology"
DOI: 10.1111/aji.13409
Abstract: The miRNAs show placenta‐specific expression patterns, which alter during pregnancy‐related complications. In present study, the role of miR‐27b‐5p during forskolin‐mediated BeWo cells fusion has been investigated. read more here.
Keywords: inhibits bewo; bewo cells; cells fusion; 27b inhibits ... See more keywords
Abstract P194: Metabolic effects of GDF15 and Activin A on trophoblasts
Sign Up to like & getrecommendations! Published in 2024 at "Hypertension"
DOI: 10.1161/hyp.81.suppl_1.p194
Abstract: Preeclampsia (PE), a pregnancy-related complication, is a major cause of maternal and fetal morbidity and mortality. The pathophysiology is not fully elucidated. Activin A and GDF15 are part of the TGFβ superfamily and markers for… read more here.
Keywords: p194 metabolic; metabolic effects; abstract p194; activin gdf15 ... See more keywords
Delta‐9‐tetrahydrocannabinol disrupts mitochondrial function and attenuates syncytialization in human placental BeWo cells
Sign Up to like & getrecommendations! Published in 2020 at "Physiological Reports"
DOI: 10.14814/phy2.14476
Abstract: The psychoactive component in cannabis, delta‐9‐tetrahydrocannabinol, can restrict fetal growth and development. Delta‐9‐tetrahydrocannabinol has been shown to negatively impact cellular proliferation and target organelles like the mitochondria resulting in reduced cellular respiration. In the placenta,… read more here.
Keywords: bewo cells; delta tetrahydrocannabinol; tetrahydrocannabinol; human placental ... See more keywords
Upregulation of microRNA-3687 promotes gestational diabetes mellitus by inhibiting follistatin-like 3
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Perinatal Medicine"
DOI: 10.1515/jpm-2024-0509
Abstract: Abstract Objectives Pregnancy-related medical complications such as gestational diabetes mellitus (GDM) are common and associated with several obstetric and neonatal problems. There is growing evidence that microRNAs (miRNAs) are essential players in the pathophysiology of… read more here.
Keywords: high throughput; mir 3687; gestational diabetes; diabetes mellitus ... See more keywords
Transport and Toxicity of Methylmercury-Cysteine in Cultured BeWo Cells
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23010394
Abstract: Mercury is a heavy metal toxicant that is prevalent throughout the environment. Organic forms of mercury, such as methylmercury (MeHg), can cross the placenta and can lead to lasting detrimental effects in the fetus. The… read more here.
Keywords: transport toxicity; bewo cells; methylmercury cysteine; mehg ... See more keywords
The Effects of 5,6,7,8,3′,4′-Hexamethoxyflavone on Apoptosis of Cultured Human Choriocarcinoma Trophoblast Cells
Sign Up to like & getrecommendations! Published in 2020 at "Molecules"
DOI: 10.3390/molecules25040946
Abstract: 5,6,7,8,3,4′-Hexamethoxyflavone, also called nobiletin (NOB), widely found in the citrus peel, is one of the main byproducts in citrus processing. NOB is considered safe, but its safety for women during pregnancy is unknown. Therefore, the… read more here.
Keywords: apoptosis; bewo cells; human choriocarcinoma; trophoblast cells ... See more keywords