Beyond antibodies: ankyrins and DARPins. From basic research to drug approval.
Sign Up to like & getrecommendations! Published in 2020 at "Current opinion in pharmacology"
DOI: 10.1016/j.coph.2020.05.004
Abstract: This Pharmacological Perspective describes the pathway that, starting from the deep understanding of ankyrins - a family of proteins with high variability-binding and high specificity-binding characteristics - led to the development of a new class… read more here.
Keywords: antibodies ankyrins; darpins basic; ankyrins darpins; beyond antibodies ... See more keywords
Beyond antibodies: B cells in Hidradenitis Suppurativa: Bystanders, contributors or therapeutic targets?
Sign Up to like & getrecommendations! Published in 2020 at "Experimental Dermatology"
DOI: 10.1111/exd.14092
Abstract: Hidradenitis Suppurativa (HS) is a chronic inflammatory dermatosis in which B cells play a prominent but unclear role. Our understanding of the role of B cells in innate and adaptive immunity (including antibody production, antigen… read more here.
Keywords: bystanders contributors; antibodies cells; hidradenitis suppurativa; beyond antibodies ... See more keywords
Vaccines beyond antibodies: Spurred by pandemic research, are T-cell vaccines moving closer to reality?
Sign Up to like & getrecommendations! Published in 2021 at "EMBO reports"
DOI: 10.15252/embr.202154073
Abstract: Lessons learned from the vaccines against SARS-CoV-2 has encouraged research and vaccine development aimed at mustering strong T cell responses against the pathogen. read more here.
Keywords: vaccines beyond; research; beyond antibodies; antibodies spurred ... See more keywords