Beyond the Bone: A Case Report and Review of Literature of Extraskeletal Chondroblastic Osteosarcoma of the Scalp
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DOI: 10.1055/s-0045-1802638
Abstract: Abstract Extraskeletal osteosarcoma (EOS) of the scalp is an extremely rare malignant mesenchymal tumor that accounts for approximately 1 to 2% of all soft tissue sarcoma and 2 to 4% of all osteosarcoma. A 40-year-old… read more here.
Keywords: chondroblastic osteosarcoma; report; osteosarcoma; osteosarcoma scalp ... See more keywords
Cathepsin K: The Action in and Beyond Bone
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DOI: 10.3389/fcell.2020.00433
Abstract: Cathepsin K (CatK) is one of the most potent proteases in lysosomal cysteine proteases family, of which main function is to mediate bone resorption. Currently, CatK is among the most attractive targets for anti-osteoporosis drug… read more here.
Keywords: catk; beyond bone; cathepsin; bone ... See more keywords
Beyond Bone Remodeling: Denosumab’s Multisystemic Benefits in Musculoskeletal Health, Metabolism, and Age-Related Diseases—A Narrative Review
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DOI: 10.3390/biomedicines13030732
Abstract: Background: Denosumab, a receptor activator of nuclear factor kappa-Β ligand (RANKL) inhibitor, demonstrates therapeutic effects beyond traditional osteoporosis management through the RANK/RANKL/osteoprotegerin pathway. Methods: This narrative review analyzed 37 studies (2018–2024) examining denosumab’s broader physiological… read more here.
Keywords: risk; bone remodeling; beyond bone; metabolism ... See more keywords