Beyond Competitive Binding: New Biochemical Insights Challenge Endocrine Disrupting Chemical Screening Paradigms.
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DOI: 10.1021/acs.est.5c07050
Abstract: Endocrine-disrupting chemicals (EDCs) pose significant health risks at environmentally relevant levels. Global screening efforts have predominantly relied on competitive binding assays. Here, using biochemical assays and computational simulations, we identified a crucial but largely overlooked… read more here.
Keywords: new biochemical; beyond competitive; biochemical insights; endocrine disrupting ... See more keywords