Articles with "bezafibrate" as a keyword



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Sunlight driven photolytic ozonation as an advanced oxidation process in the oxidation of bezafibrate, cotinine and iopamidol.

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Published in 2019 at "Water research"

DOI: 10.1016/j.watres.2018.12.013

Abstract: This study investigates the efficacy of the system O3/sunlight radiation compared to dark ozonation when treating pharmaceuticals compounds of different reactivity, namely bezafibrate, cotinine, and iopamidol. Results show the beneficial effects of simulated sunlight radiation… read more here.

Keywords: bezafibrate; oxidation; cotinine iopamidol; iopamidol ... See more keywords
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P39 Real world experience of using bezafibrate for PBC

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Published in 2020 at "Gut"

DOI: 10.1136/gutjnl-2020-basl.49

Abstract: Primary Biliary Cholangitis (PBC) is a rare autoimmune condition with an incidence of 20–40 cases per 100,000. Levels of alkaline phosphatase (ALP) can be used as a surrogate marker of clinical response to pharmacotherapy. Ursodeoxycholic… read more here.

Keywords: therapy; bezafibrate; bzf; real world ... See more keywords
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Prevention of Elevation in Plasma Triacylglycerol with High-Dose Bezafibrate Treatment Abolishes Insulin Resistance and Attenuates Glucose Intolerance Induced by Short-Term Treatment with Dexamethasone in Rats

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Published in 2018 at "International Journal of Endocrinology"

DOI: 10.1155/2018/3257812

Abstract: Objective Fibrates are used as lipid-lowering drugs and are well tolerated as cotreatments when glucose metabolism disturbances are also present. Synthetic glucocorticoids (GCs) are diabetogenic drugs that cause dyslipidemia, dysglycemia, glucose intolerance, and insulin resistance… read more here.

Keywords: bezafibrate; glucose intolerance; treatment; insulin resistance ... See more keywords
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Effect of Bezafibrate, a PPARα Activator, on Acute and Subacute Inflammation in Male Wistar Rats

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Published in 2023 at "Journal of Pharmacology and Pharmacotherapeutics"

DOI: 10.1177/0976500x231175218

Abstract: To investigate the anti-inflammatory effect of bezafibrate on acute and subacute inflammation in adult male Wistar rats. The study was carried out in adult male Wistar rats and they were allocated into three groups, that… read more here.

Keywords: inflammation; effect; subacute inflammation; bezafibrate ... See more keywords
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Bezafibrate Ameliorates Arterial Stiffness Assessed by Cardio-Ankle Vascular Index in Hypertriglyceridemic Patients with Type 2 Diabetes Mellitus

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Published in 2018 at "Journal of Atherosclerosis and Thrombosis"

DOI: 10.5551/jat.45799

Abstract: Aim: Cardio-ankle vascular index (CAVI) reflects arterial stiffness and has been established as a useful surrogate marker of atherosclerosis. Contrary to the abundant data indicating slower progression of atherosclerosis with statins, studies on fibrates remain… read more here.

Keywords: bezafibrate; patients type; group; hypertriglyceridemic patients ... See more keywords
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Efficacy and Safety of Pemafibrate Versus Bezafibrate to Treat Patients with Hypertriglyceridemia: A Randomized Crossover Study

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Published in 2022 at "Journal of Atherosclerosis and Thrombosis"

DOI: 10.5551/jat.63659

Abstract: Aim: Pemafibrate is a highly selective agonist for peroxisome proliferator-activated receptor (PPAR)-α, a key regulator of lipid and glucose metabolism. We compared the efficacy and safety of pemafibrate with those of bezafibrate, a nonselective PPAR-α… read more here.

Keywords: pemafibrate; safety pemafibrate; randomized crossover; pemafibrate bezafibrate ... See more keywords