Abstract LB-317: Identification of a novel preclinical candidate for CDK7 inhibition
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DOI: 10.1158/1538-7445.am2017-lb-317
Abstract: Cyclin-dependent kinase 7 (CDK7) is an important constituent of the cellular transcriptional machinery, where it phosphorylates the C-terminal domain (CTD) of RNAP polymerase II (RNAPII). Because many tumor types are critically dependent on transcription for… read more here.
Keywords: cdk7; candidate; inhibition; cancer ... See more keywords