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Safety and Activity of the Highly Specific BTK Inhibitor BGB-3111 in Combination with the PD-1 Inhibitor BGB-A317 in Patients with B-Cell Lymphoid Malignancies

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Published in 2017 at "Blood"

DOI: 10.1182/blood.v130.suppl_1.4057.4057

Abstract: Introduction BGB-3111 is a potent, highly specific, and irreversible Bruton tyrosine kinase (BTK) inhibitor, with greater selectivity for BTK vs other TEC- and EGFR-family kinases, and demonstrates favorable pharmacokinetic and pharmacodynamics properties (Tam et al.… read more here.

Keywords: bgb a317; combination; bgb; research funding ... See more keywords