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   Articles with "bgr" as a keyword



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Association of Retinoic Acid Receptor &bgr; Gene With Onset and Progression of Lichen Sclerosus–Associated Vulvar Squamous Cell Carcinoma

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recommendations! Published in 2018 at "JAMA Dermatology"

DOI: 10.1001/jamadermatol.2018.1373

Abstract: Importance Molecular alterations in lichen sclerosus–associated vulvar squamous cell carcinoma (LS-VSCC) are largely unknown. Objective To determine whether the retinoic acid receptor &bgr; (RAR&bgr;) tumor-suppressor gene is involved in the onset and/or progression of LS-VSCC.… read more here.

Keywords: bgr; rar bgr; vscc; normal skin ... See more keywords
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Association of &bgr;-Amyloid and Apolipoprotein E &egr;4 With Memory Decline in Preclinical Alzheimer Disease

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recommendations! Published in 2018 at "JAMA Neurology"

DOI: 10.1001/jamaneurol.2017.4325

Abstract: Importance Older age, high levels of &bgr;-amyloid (A&bgr;), and the presence of the apolipoprotein E (APOE) &egr;4 allele are risk factors for Alzheimer disease (AD). However, the extent to which increasing age, A&bgr;, and &egr;4… read more here.

Keywords: memory decline; age; bgr; egr ... See more keywords
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Association of Excessive Daytime Sleepiness With Longitudinal &bgr;-Amyloid Accumulation in Elderly Persons Without Dementia

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recommendations! Published in 2018 at "JAMA Neurology"

DOI: 10.1001/jamaneurol.2018.0049

Abstract: Importance Aging is associated with excessive daytime sleepiness (EDS), which has been linked to cognitive decline in the elderly. However, whether EDS is associated with the pathologic processes of Alzheimer disease remains unclear. Objective To… read more here.

Keywords: accumulation; bgr; excessive daytime; cingulate ... See more keywords
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Food and water intake, body temperature and metabolic consequences of interleukin-1β microinjection into the cingulate cortex of the rat

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recommendations! Published in 2017 at "Behavioural Brain Research"

DOI: 10.1016/j.bbr.2017.05.041

Abstract: HighlightsInterleukin‐1&bgr; (IL‐1&bgr;) was microinjected into the cingulate cortex (cctx) of the rat.IL‐1&bgr; caused significant elevation of body temperature.Paracetamol pretreatment attenuated the hyperthermic effect of IL‐1&bgr;.IL‐1&bgr; caused significant decrease of HDL and total cholesterol. Abstract In… read more here.

Keywords: food water; bgr; cingulate cortex; body temperature ... See more keywords
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Diabetes mellitus and Alzheimer’s disease: GSK-3β as a potential link

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recommendations! Published in 2018 at "Behavioural Brain Research"

DOI: 10.1016/j.bbr.2017.11.015

Abstract: HIGHLIGHTSGSK‐3&bgr; is involved in the physiological and pathological progress of DM and AD respectively.In DM, GSK‐3&bgr; is one of the key factors leading to insulin deficiency and insulin resistance.In AD, GSK‐3&bgr; plays an important role… read more here.

Keywords: insulin; gsk bgr; bgr; potential link ... See more keywords
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Mifepristone attenuates depression-like changes induced by chronic central administration of interleukin-1β in rats

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recommendations! Published in 2018 at "Behavioural Brain Research"

DOI: 10.1016/j.bbr.2018.03.033

Abstract: HighlightsIL‐1&bgr; increased the levels of pro‐BDNF, but decreased GDNF and GFR&agr;1 in the amygdale.RU486 improved the depression‐like behaviors induced by IL‐1&bgr;.RU486 differently regulated the function of microglia and astrocyte. ABSTRACT Increased proinflammatory cytokines, such as… read more here.

Keywords: depression; gfr agr; bgr; changes induced ... See more keywords
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Nociceptin/orphanin FQ antagonizes lipopolysaccharide‐stimulated proliferation, migration and inflammatory signaling in human glioblastoma U87 cells

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recommendations! Published in 2017 at "Biochemical Pharmacology"

DOI: 10.1016/j.bcp.2017.05.021

Abstract: &NA; Glioblastoma is among the most aggressive brain tumors and has an exceedingly poor prognosis. Recently, the importance of the tumor microenvironment in glioblastoma cell growth and progression has been emphasized. Toll‐like receptor 4 (TLR4)… read more here.

Keywords: u87 cells; bgr; glioblastoma; proliferation ... See more keywords
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Free‐fatty acid receptor‐4 (FFA4) modulates ROS generation and COX‐2 expression via the C‐terminal &bgr;‐arrestin phosphosensor in Raw 264.7 macrophages

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recommendations! Published in 2017 at "Biochemical Pharmacology"

DOI: 10.1016/j.bcp.2017.09.008

Abstract: Graphical abstract Figure. No Caption available. ABSTRACT Agonism of the G protein‐coupled free‐fatty acid receptor‐4 (FFA4) has been shown to promote numerous anti‐inflammatory effects in macrophages that arise due to interaction with &bgr;‐arrestin partner proteins.… read more here.

Keywords: bgr arrestin; ffa4; bgr; arrestin phosphosensor ... See more keywords
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Increased systemic and epidermal levels of IL‐17A and IL‐1&bgr; promotes progression of non‐segmental vitiligo

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recommendations! Published in 2017 at "Cytokine"

DOI: 10.1016/j.cyto.2016.12.014

Abstract: BACKGROUND Non‐segmental vitiligo (NSV) results from autoimmune destruction of melanocytes. The altered levels of various cytokines have been proposed in the pathogenesis of vitiligo. However, the exact immune mechanisms have not yet been fully elucidated.… read more here.

Keywords: levels 17a; vitiligo; non segmental; bgr ... See more keywords
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CCAAT/Enhancer‐binding protein &bgr; promotes pathogenesis of EAE

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recommendations! Published in 2017 at "Cytokine"

DOI: 10.1016/j.cyto.2017.01.005

Abstract: HIGHLIGHTSCebpb−/− mice are resistant to EAE.In vivo Th17 responses are impaired in absence of C/EBP&bgr;.Th17 differentiation is normal in APC‐free cultures.C/EBP&bgr; binds to the IL‐23R in myeloid and Th17 cells. ABSTRACT The CCAAT/Enhancer Binding Protein… read more here.

Keywords: ccaat enhancer; ebp bgr; bgr; eae ... See more keywords
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IL‐33‐matured dendritic cells promote Th17 cell responses via IL‐1&bgr; and IL‐6

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recommendations! Published in 2017 at "Cytokine"

DOI: 10.1016/j.cyto.2017.07.022

Abstract: Graphical abstract Figure. No Caption available. HighlightsIL33 enhances Th17 cell differentiation through DC maturation.IL33 does not directly induce differentiation of naïve CD4+ T cells to Th17 cells.IL33‐matDCs increase surface molecule‐expressions driving T cell activation.IL33‐matDCs promote… read more here.

Keywords: cell responses; bgr; responses via; th17 cell ... See more keywords