Mirabegron, a &bgr;3‐adrenoceptor agonist reduced platelet aggregation through cyclic adenosine monophosphate accumulation
Sign Up to like & getrecommendations! Published in 2018 at "European Journal of Pharmacology"
DOI: 10.1016/j.ejphar.2018.04.010
Abstract: &NA; Mirabegron is a &bgr;3‐adrenoceptor agonist and released on the marked for the treatment of overactive bladder. Because mirabegron is the only &bgr;3‐adrenoceptor agonist available and substances that increase the levels of cyclic adenosine monophosphate… read more here.
Keywords: platelet aggregation; mirabegron; bgr adrenoceptor;
Brain cholesterol metabolite 24‐hydroxycholesterol modulates inotropic responses to &bgr;‐adrenoceptor stimulation: The role of NO and phosphodiesterase
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DOI: 10.1016/j.lfs.2019.01.054
Abstract: Aims: 24‐Hydroxycholesterol (24HC) is the main brain cholesterol metabolite, which level in the circulation is significantly changed under physiological and pathological conditions. Here, we have studied the effect of 24HC on the inotropic responses to… read more here.
Keywords: bgr; phosphodiesterase; responses bgr; adrenoceptor stimulation ... See more keywords
&bgr;3 adrenergic receptor activation relaxes human corpus cavernosum and penile artery through a hydrogen sulfide/cGMP‐dependent mechanism
Sign Up to like & getrecommendations! Published in 2017 at "Pharmacological Research"
DOI: 10.1016/j.phrs.2017.07.025
Abstract: Graphical abstract Figure. No caption available. ABSTRACT Erectile function is a widely accepted indicator of systemic endothelial activity since from a clinical standpoint erectile dysfunction (ED) often precedes cardiovascular events. Recently it has been described… read more here.
Keywords: cgmp; bgr adrenoceptor; bgr; penile artery ... See more keywords