Targeting the Dvl-1/β-arrestin2/JNK3 interaction disrupts Wnt5a-JNK3 signaling and protects hippocampal CA1 neurons during cerebral ischemia reperfusion
Sign Up to like & getrecommendations! Published in 2018 at "Neuropharmacology"
DOI: 10.1016/j.neuropharm.2018.03.006
Abstract: &NA; It is well known that Wnt5a activation plays a pivotal role in brain injury and &bgr;‐arrestin2 induces c‐Jun N‐terminal kinase (JNK3) activation is involved in neuronal cell death. Nonetheless, the relationship between Wnt5a and… read more here.
Keywords: arrestin2; jnk3 signaling; bgr arrestin2; jnk3 ... See more keywords
MAS1 Receptor Trafficking Involves ERK1/2 Activation Through a &bgr;-Arrestin2–Dependent Pathway
Sign Up to like & getrecommendations! Published in 2017 at "Hypertension"
DOI: 10.1161/hypertensionaha.117.09789
Abstract: The MAS1 receptor (R) exerts protective effects in the brain, heart, vessels, and kidney. R trafficking plays a critical function in signal termination and propagation and in R resensitization. We examined MAS1R internalization and trafficking… read more here.
Keywords: stimulation; bgr arrestin2; erk1 activation; activation ... See more keywords