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   Articles with "bgr catenin" as a keyword



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Andrographolide derivative ameliorates dextran sulfate sodium‐induced experimental colitis in mice

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recommendations! Published in 2019 at "Biochemical Pharmacology"

DOI: 10.1016/j.bcp.2019.03.019

Abstract: Graphical abstract Figure. No caption available. &NA; The therapeutic efficacy of immunosuppressive agents has been intensively studied for colitis management. We synthesized a series of andrographolide derivatives and reported their structure‐activity‐relationship and anti‐inflammatory activity in… read more here.

Keywords: bgr catenin; dextran sulfate; sulfate sodium; colitis ... See more keywords
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STAT3 suppresses Wnt/&bgr;‐catenin signaling during the induction phase of primary Myf5+ brown adipogenesis

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recommendations! Published in 2018 at "Cytokine"

DOI: 10.1016/j.cyto.2018.05.023

Abstract: HighlightsSTAT3 is required during the induction phase for differentiation of primary brown pre‐adipocytes.Deletion of STAT3 after the induction period does not affect UCP1 protein levels and differentiation.STAT3 KO cells can be rescued through inhibition of… read more here.

Keywords: bgr catenin; catenin; stat3; differentiation ... See more keywords
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Characterization and function of a &bgr;‐catenin homolog from Litopenaeus vannamei in WSSV infection

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recommendations! Published in 2017 at "Developmental and Comparative Immunology"

DOI: 10.1016/j.dci.2017.07.003

Abstract: Abstract As a conserved signaling pathway, Wnt/&bgr;‐catenin signaling pathway participates in many physiological activities, including cell differentiation, apoptosis and so on. &bgr;‐catenin is the key molecule of Wnt/&bgr;‐catenin signaling pathway and plays a pivotal role.… read more here.

Keywords: wssv infection; bgr catenin; catenin; catenin homolog ... See more keywords
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Paracrine Wnt5a‐&bgr;‐Catenin Signaling Triggers a Metabolic Program that Drives Dendritic Cell Tolerization

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recommendations! Published in 2018 at "Immunity"

DOI: 10.1016/j.immuni.2017.12.004

Abstract: Summary Despite recent advances, many cancers remain refractory to available immunotherapeutic strategies. Emerging evidence indicates that the tolerization of local dendritic cells (DCs) within the tumor microenvironment promotes immune evasion. Here, we have described a… read more here.

Keywords: bgr catenin; pathway; bgr; wnt5a bgr ... See more keywords
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Platelet‐rich plasma inhibits Wnt/&bgr;‐catenin signaling in rabbit cartilage cells activated by IL‐1&bgr;

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recommendations! Published in 2018 at "International Immunopharmacology"

DOI: 10.1016/j.intimp.2017.12.031

Abstract: Objective: Platelet‐rich plasma (PRP) has been reported to alleviate degenerative pathological damage to joint cartilage. This study aimed to investigate the effect of PRP on Wnt/&bgr;‐catenin signaling in rabbit chondrocytes. Methods: Using 3‐month‐old New Zealand… read more here.

Keywords: bgr catenin; bgr; wnt bgr; prp ... See more keywords
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Pimozide suppresses colorectal cancer via inhibition of Wnt/&bgr;‐catenin signaling pathway

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recommendations! Published in 2018 at "Life Sciences"

DOI: 10.1016/j.lfs.2018.08.027

Abstract: Objective: Wnt/&bgr;‐catenin signaling pathway plays important role in colorectal cancer (CRC) and acts as a potential therapeutic target. Pimozide is a FDA‐approved clinical drug used to treat psychotic diseases and it has shown anticancer effect… read more here.

Keywords: bgr catenin; catenin signaling; catenin; signaling pathway ... See more keywords
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miR‐126‐3p sensitizes glioblastoma cells to temozolomide by inactivating Wnt/&bgr;‐catenin signaling via targeting SOX2

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recommendations! Published in 2019 at "Life Sciences"

DOI: 10.1016/j.lfs.2019.04.023

Abstract: Aims: The acquired drug resistance has been regarded as a main barrier for the effective treatment of temozolomide (TMZ) in glioblastoma (GBM). MiR‐126‐3p is commonly down‐regulated and exerts tumor‐suppressive roles in kinds of human cancers,… read more here.

Keywords: bgr catenin; mir 126; gbm; catenin signaling ... See more keywords
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Salvianolic acid A alleviates chronic ethanol‐induced liver injury via promotion of &bgr;‐catenin nuclear accumulation by restoring SIRT1 in rats

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recommendations! Published in 2018 at "Toxicology and Applied Pharmacology"

DOI: 10.1016/j.taap.2018.04.036

Abstract: ABSTRACT In recent years, alcoholic liver disease (ALD) has emerged as a growing public health problem worldwide. &bgr;‐catenin plays an important role in the growth, development, regeneration and metabolic activity of the liver. Salvianolic acid… read more here.

Keywords: liver injury; bgr catenin; catenin; induced liver ... See more keywords
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Matrix metalloproteinase 9 is associated with peritoneal membrane solute transport and induces angiogenesis through &bgr;-catenin signaling

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recommendations! Published in 2017 at "Nephrology Dialysis Transplantation"

DOI: 10.1093/ndt/gfw076

Abstract: Background. For patients using peritoneal dialysis (PD), the peritoneal membrane can develop fibrosis and angiogenesis, leading to ultrafiltration failure, chronic hypervolemia and increased risk of technique failure and mortality. Matrix metalloproteinases (MMPs), and specifically the… read more here.

Keywords: peritoneal membrane; bgr catenin; mmp9;
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Hypermethylation of multiple Wnt antagonist genes in gastric neoplasia

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recommendations! Published in 2018 at "Medicine"

DOI: 10.1097/md.0000000000013734

Abstract: Abstract Wnt antagonist genes hypermethylation has been found in several tumors. Accordingly, the events that occur during the progression of adenoma to carcinoma have been characterized and include activation of the Wnt-pathway. Further, gastric adenoma… read more here.

Keywords: wnt antagonist; bgr catenin; hypermethylation; antagonist genes ... See more keywords
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Paracrine osteoprotegerin and &bgr;-catenin stabilization support synovial sarcomagenesis in periosteal cells

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recommendations! Published in 2018 at "Journal of Clinical Investigation"

DOI: 10.1172/jci94955

Abstract: Synovial sarcoma (SS) is an aggressive soft-tissue sarcoma that is often discovered during adolescence and young adulthood. Despite the name, synovial sarcoma does not typically arise from a synoviocyte but instead arises in close proximity… read more here.

Keywords: bgr catenin; synovial sarcomagenesis; periosteal cells; ss18 ssx ... See more keywords