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Published in 2019 at "Biochemical Pharmacology"
DOI: 10.1016/j.bcp.2019.03.019
Abstract: Graphical abstract Figure. No caption available. &NA; The therapeutic efficacy of immunosuppressive agents has been intensively studied for colitis management. We synthesized a series of andrographolide derivatives and reported their structure‐activity‐relationship and anti‐inflammatory activity in…
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Keywords:
bgr catenin;
dextran sulfate;
sulfate sodium;
colitis ... See more keywords
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Published in 2018 at "Cytokine"
DOI: 10.1016/j.cyto.2018.05.023
Abstract: HighlightsSTAT3 is required during the induction phase for differentiation of primary brown pre‐adipocytes.Deletion of STAT3 after the induction period does not affect UCP1 protein levels and differentiation.STAT3 KO cells can be rescued through inhibition of…
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Keywords:
bgr catenin;
catenin;
stat3;
differentiation ... See more keywords
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Published in 2017 at "Developmental and Comparative Immunology"
DOI: 10.1016/j.dci.2017.07.003
Abstract: Abstract As a conserved signaling pathway, Wnt/&bgr;‐catenin signaling pathway participates in many physiological activities, including cell differentiation, apoptosis and so on. &bgr;‐catenin is the key molecule of Wnt/&bgr;‐catenin signaling pathway and plays a pivotal role.…
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Keywords:
wssv infection;
bgr catenin;
catenin;
catenin homolog ... See more keywords
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Published in 2018 at "Immunity"
DOI: 10.1016/j.immuni.2017.12.004
Abstract: Summary Despite recent advances, many cancers remain refractory to available immunotherapeutic strategies. Emerging evidence indicates that the tolerization of local dendritic cells (DCs) within the tumor microenvironment promotes immune evasion. Here, we have described a…
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Keywords:
bgr catenin;
pathway;
bgr;
wnt5a bgr ... See more keywords
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Published in 2018 at "International Immunopharmacology"
DOI: 10.1016/j.intimp.2017.12.031
Abstract: Objective: Platelet‐rich plasma (PRP) has been reported to alleviate degenerative pathological damage to joint cartilage. This study aimed to investigate the effect of PRP on Wnt/&bgr;‐catenin signaling in rabbit chondrocytes. Methods: Using 3‐month‐old New Zealand…
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Keywords:
bgr catenin;
bgr;
wnt bgr;
prp ... See more keywords
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Published in 2018 at "Life Sciences"
DOI: 10.1016/j.lfs.2018.08.027
Abstract: Objective: Wnt/&bgr;‐catenin signaling pathway plays important role in colorectal cancer (CRC) and acts as a potential therapeutic target. Pimozide is a FDA‐approved clinical drug used to treat psychotic diseases and it has shown anticancer effect…
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Keywords:
bgr catenin;
catenin signaling;
catenin;
signaling pathway ... See more keywords
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Published in 2019 at "Life Sciences"
DOI: 10.1016/j.lfs.2019.04.023
Abstract: Aims: The acquired drug resistance has been regarded as a main barrier for the effective treatment of temozolomide (TMZ) in glioblastoma (GBM). MiR‐126‐3p is commonly down‐regulated and exerts tumor‐suppressive roles in kinds of human cancers,…
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Keywords:
bgr catenin;
mir 126;
gbm;
catenin signaling ... See more keywords
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Published in 2018 at "Toxicology and Applied Pharmacology"
DOI: 10.1016/j.taap.2018.04.036
Abstract: ABSTRACT In recent years, alcoholic liver disease (ALD) has emerged as a growing public health problem worldwide. &bgr;‐catenin plays an important role in the growth, development, regeneration and metabolic activity of the liver. Salvianolic acid…
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Keywords:
liver injury;
bgr catenin;
catenin;
induced liver ... See more keywords
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Published in 2017 at "Nephrology Dialysis Transplantation"
DOI: 10.1093/ndt/gfw076
Abstract: Background. For patients using peritoneal dialysis (PD), the peritoneal membrane can develop fibrosis and angiogenesis, leading to ultrafiltration failure, chronic hypervolemia and increased risk of technique failure and mortality. Matrix metalloproteinases (MMPs), and specifically the…
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Keywords:
peritoneal membrane;
bgr catenin;
mmp9;
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Published in 2018 at "Medicine"
DOI: 10.1097/md.0000000000013734
Abstract: Abstract Wnt antagonist genes hypermethylation has been found in several tumors. Accordingly, the events that occur during the progression of adenoma to carcinoma have been characterized and include activation of the Wnt-pathway. Further, gastric adenoma…
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Keywords:
wnt antagonist;
bgr catenin;
hypermethylation;
antagonist genes ... See more keywords
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Published in 2018 at "Journal of Clinical Investigation"
DOI: 10.1172/jci94955
Abstract: Synovial sarcoma (SS) is an aggressive soft-tissue sarcoma that is often discovered during adolescence and young adulthood. Despite the name, synovial sarcoma does not typically arise from a synoviocyte but instead arises in close proximity…
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Keywords:
bgr catenin;
synovial sarcomagenesis;
periosteal cells;
ss18 ssx ... See more keywords