Immunomodulatory effects of M2000 (&bgr;‐D‐Mannuronic acid) on TNF‐&agr;, IL‐17 and FOXP3 gene expression in patients with inflammatory bowel disease
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DOI: 10.1016/j.intimp.2017.08.011
Abstract: Introduction Inflammatory bowel diseases (IBD) are immune‐mediated disorders that result from an aberrant immunological response to the gut luminal antigen in genetically susceptible patients. IBD is categorized into two serotype, Crohn's diseases (CD) and ulcerative… read more here.
Keywords: bgr mannuronic; tnf agr; mannuronic acid; expression ... See more keywords
Evaluation of the efficacy and safety of &bgr;‐d‐mannuronic acid in patients with ankylosing spondylitis: A 12‐week randomized, placebo‐controlled, phase I/II clinical trial
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DOI: 10.1016/j.intimp.2017.11.003
Abstract: Objective To evaluate the efficacy, safety and tolerability of &bgr;‐d‐mannuronic acid (M2000) in the treatment of ankylosing spondylitis (AS). Methods The study was a 12‐week randomized, double‐blind, placebo‐controlled, phase I/II clinical trial with 3 treatment… read more here.
Keywords: placebo; week; bgr mannuronic; mannuronic acid ... See more keywords