Trans‐4‐methoxy‐&bgr;‐nitrostyrene relaxes rat thoracic aorta through a sGC‐dependent pathway
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DOI: 10.1016/j.ejphar.2017.05.007
Abstract: Abstract 1‐Nitro‐2‐phenylethene (NPe) induces a more potent vasorelaxant effect in rat aorta than its structural analog 1‐nitro‐2‐phenylethane, but mediated through a different mechanism, independent of soluble guanylate cyclase (sGC) stimulation. We hypothesized that introducing an… read more here.
Keywords: trans methoxy; bgr nitrostyrene; methoxy bgr; pathway ... See more keywords
3′‐Hydroxy‐4′‐methoxy‐&bgr;‐methyl‐&bgr;‐nitrostyrene inhibits tumor growth through ROS generation and GSH depletion in lung cancer cells
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DOI: 10.1016/j.lfs.2016.12.009
Abstract: Aims: Members of the &bgr;‐nitrostyrene family are known to suppress tumor growth, with the underlying mechanisms of &bgr;‐nitrostyrene remain mostly unclear. Herein, we synthesized a &bgr;‐nitrostyrene derivative, 3′‐hydroxy‐4′‐methoxy‐&bgr;‐methyl‐&bgr;‐nitrostyrene (CYT‐Rx20), and explored its anticancer activities in… read more here.
Keywords: cyt rx20; bgr; lung cancer; bgr nitrostyrene ... See more keywords