Database and Bioinformatic Analysis of BCL-2 Family Proteins and BH3-Only Proteins.
Sign Up to like & getrecommendations! Published in 2019 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-8861-7_2
Abstract: BCL-2 proteins correspond to a structurally, functionally, and phylogenetically heterogeneous group of regulators that play crucial roles in the life and death of animal cells. Some of these regulators also represent therapeutic targets in human… read more here.
Keywords: bh3 proteins; database bioinformatic; analysis; analysis bcl ... See more keywords
Differences in the Association of BH3-Only Proteins to Biological Membranes
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DOI: 10.1016/j.bpj.2016.11.1135
Abstract: Apoptosis, a prevalent mechanism of programmed cell death, is regulated by the Bcl-2 protein family. The balance between pro- and anti-apoptotic Bcl-2 members in the mitochondrial outer membrane (MOM) protects or triggers MOM permeabilization. Bcl-2… read more here.
Keywords: bh3 proteins; bh3; differences association; association bh3 ... See more keywords
Characterization of an alternative BAK-binding site for BH3 peptides
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DOI: 10.1038/s41467-020-17074-y
Abstract: Many cellular stresses are transduced into apoptotic signals through modification or up-regulation of the BH3-only subfamily of BCL2 proteins. Through direct or indirect mechanisms, these proteins activate BAK and BAX to permeabilize the mitochondrial outer… read more here.
Keywords: bmf hrk; directly activate; bh3 proteins; bh3 ... See more keywords