Loss of the basic helix-loop-helix transcription factor Bhlhe41 induces cell death and impairs neurite outgrowth in Neuro2a cells
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DOI: 10.1007/s11010-018-3383-z
Abstract: The basic helix-loop-helix (bHLH) superfamily of transcription factors have been implicated in a wide range of cellular functions such as proliferation, differentiation, tumorigenesis, and circadian rhythms. In a previous siRNA-based screen, bHLH family member e41… read more here.
Keywords: bhlhe41; loop helix; helix loop; neurite outgrowth ... See more keywords
BHLHE41 inhibits bladder cancer progression via regulation of PYCR1 stability and thus inactivating PI3K/AKT signaling pathway
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DOI: 10.1186/s40001-024-01889-2
Abstract: The basic helix-loop-helix family member e41 (BHLHE41) is frequently dysregulated in tumors and plays a crucial role in malignant progression of various cancers. Nevertheless, its specific function and underlying mechanism in bladder cancer (BCa) remain… read more here.
Keywords: bhlhe41; pi3k akt; bladder cancer; pycr1 ... See more keywords