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   Articles with "bhmt" as a keyword



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The BHMT-betaine methylation pathway epigenetically modulates oligodendrocyte maturation

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recommendations! Published in 2021 at "PLoS ONE"

DOI: 10.1371/journal.pone.0250486

Abstract: Research into the epigenome is of growing importance as a loss of epigenetic control has been implicated in the development of neurodegenerative diseases. Previous studies have implicated aberrant DNA and histone methylation in multiple sclerosis… read more here.

Keywords: betaine methylation; bhmt; betaine; bhmt betaine ... See more keywords
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Exploring effects of betaine-homocysteine methyltransferase (BHMT) gene polymorphisms on fatty acid traits and cholesterol in sheep

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recommendations! Published in 2019 at "Journal of the Indonesian Tropical Animal Agriculture"

DOI: 10.14710/jitaa.44.3.243-251

Abstract: This study was aimed to explore the effects of Betaine-Homocysteine Methyltransferase (BHMT) gene polymorphisms on fatty acid traits and cholesterol in lambs. This study used a total of 147 blood samples for genotyping including 19… read more here.

Keywords: acid traits; bhmt; fatty acid; bhmt gene ... See more keywords
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Vegetable Oil-Peroxidation Product ‘Hydroxynonenal’ Causes Hepatocyte Injury and Steatosis via Hsp70.1 and BHMT Disorders in the Monkey Liver

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recommendations! Published in 2023 at "Nutrients"

DOI: 10.3390/nu15081904

Abstract: Hsp70.1 has a dual function as a chaperone protein and lysosomal stabilizer. In 2009, we reported that calpain-mediated cleavage of carbonylated Hsp70.1 causes neuronal death by inducing lysosomal rupture in the hippocampal CA1 neurons of… read more here.

Keywords: bhmt; steatosis; microscopy; hsp70 bhmt ... See more keywords
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Genetic and epigenetic regulation of BHMT is associated with folate therapy efficacy in hyperhomocysteinaemia.

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recommendations! Published in 2019 at "Asia Pacific journal of clinical nutrition"

DOI: 10.6133/apjcn.201912_28(4).0025

Abstract: BACKGROUND AND OBJECTIVES Hyperhomocysteinaemia (HHcy) is an independent risk factors for several disorders, including cardiovascular disease. The understanding of the relationship among genetic, epigenetic and the efficacy of folate therapy for HHcy remain unclear. This… read more here.

Keywords: methylation; bhmt; folate therapy; efficacy ... See more keywords