Articles with "biallelic knockout" as a keyword



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CRISPR/Cas9‐mediated single and biallelic knockout of poplar STERILE APETALA (PopSAP) leads to complete reproductive sterility

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Published in 2020 at "Plant Biotechnology Journal"

DOI: 10.1111/pbi.13451

Abstract: The spread of highly domesticated, exotic, or genetically-modified organisms into wild and feral populations and/or their genes beyond the boundaries of plantations can negatively, irreversibly impact the health of native species and pose significant management… read more here.

Keywords: mediated single; knockout poplar; crispr cas9; biallelic knockout ... See more keywords
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Abstract 5243: CRISPR knockout: How to get high biallelic knockout

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Published in 2019 at "Cancer Research"

DOI: 10.1158/1538-7445.sabcs18-5243

Abstract: Although homology directed repair (HDR)-mediated gene knockout / knockin is well established, it cannot necessarily be applied in some cell types and organisms with low HDR frequencies. Herein we describe an improved technology for genome-wide… read more here.

Keywords: crispr knockout; crispr; knockout knockin; knockout get ... See more keywords