Ionic liquid catalyzed Ritter reaction/Pd-catalyzed directed Ortho-arylation; facile access to diverse libraries of biaryl-amides from Aryl-nitriles
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DOI: 10.1016/j.tetlet.2020.152553
Abstract: Abstract Diverse libraries of biaryl-amides bearing N-t-butyl and N-adamantyl groups were synthesized in two steps by the Ritter reaction of aryl-nitriles, using tBuOH and AdaOH as carbocation precursors, and employing [BMIM(SO3H)][OTf] (neat or with [BMIM][PF6]… read more here.
Keywords: libraries biaryl; catalyzed directed; diverse libraries; biaryl amides ... See more keywords