Intrinsic bias at non-canonical, β-arrestin-coupled seven transmembrane receptors.
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DOI: 10.1016/j.molcel.2021.09.007
Abstract: G-protein-coupled receptors (GPCRs), also known as seven transmembrane receptors (7TMRs), typically interact with two distinct signal-transducers, i.e., G proteins and β-arrestins (βarrs). Interestingly, there are some non-canonical 7TMRs that lack G protein coupling but interact… read more here.
Keywords: intrinsic bias; bias non; transmembrane receptors; seven transmembrane ... See more keywords