Functionally Biased D2R Antagonists: Targeting the β-Arrestin Pathway to Improve Antipsychotic Treatment.
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DOI: 10.1021/acschembio.8b00168
Abstract: Schizophrenia is a severe neuropsychiatric disease that lacks completely effective and safe therapies. As a polygenic disorder, genetic studies have only started to shed light on its complex etiology. To date, the positive symptoms of… read more here.
Keywords: functionally biased; treatment; biased d2r; arrestin ... See more keywords