New Tricks for an Old Dog: Biased GPCR Agonism of an M4 Muscarinic Acetylcholine Receptor Antagonist in Airway Smooth Muscle Cells
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DOI: 10.1165/rcmb.2022-0335ed
Abstract: ligands, the expectation is that they will only trigger G-protein–independent pathways that promote antiremodeling and bronchorelaxant actions via b -arrestin pathways that are distinct from those driving bronchial hyperresponsiveness. The study by Tompkins provides strong… read more here.
Keywords: biased gpcr; tricks old; dog biased; old dog ... See more keywords