G protein–biased GPR3 signaling ameliorates amyloid pathology in a preclinical Alzheimer’s disease mouse model
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DOI: 10.1073/pnas.2204828119
Abstract: Significance Levels of the orphan G protein–coupled receptor GPR3 are elevated in a subset of patients with Alzheimer’s disease (AD). Our group previously showed that genetic deletion of Gpr3 attenuates amyloid-β (Aβ) pathology in multiple… read more here.
Keywords: amyloid pathology; alzheimer disease; pathology; biased gpr3 ... See more keywords