Articles with "biased ligand" as a keyword



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Single-molecule force spectroscopy study of interactions between angiotensin II type 1 receptor and different biased ligands in living cells

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Published in 2018 at "Analytical and Bioanalytical Chemistry"

DOI: 10.1007/s00216-018-0956-3

Abstract: AbstractAngiotensin II type 1 receptor (AT1R), a typical G protein-coupled receptor, plays a key role in regulating many cardiovascular functions. Different ligands can bind with AT1R to selectively activate either G protein (Gq) or β-arrestin… read more here.

Keywords: molecule; at1r; force; spectroscopy ... See more keywords