In vitro effects of sodium bicarbonate buffer on rumen fermentation, levels of lipopolysaccharide and biogenic amine, and composition of rumen microbiota.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of the science of food and agriculture"
DOI: 10.1002/jsfa.7861
Abstract: BACKGROUND Diets containing high levels of carbohydrates provoke a rapid decrease of rumen pH and high levels of biogenic amines and lipopolysaccharides (LPS), which severely impair the health and performance of ruminants. The goal of… read more here.
Keywords: bicarbonate buffer; rumen fermentation; effects sodium; buffer rumen ... See more keywords
Simple bicarbonate buffer system for dissolution testing: Floating lid method and its application to colonic drug delivery system
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Drug Delivery Science and Technology"
DOI: 10.1016/j.jddst.2021.102447
Abstract: Abstract In this study, we developed a simple and easy method to use bicarbonate buffer solutions for dissolution tests. A floating lid was newly introduced to prevent the evaporation of CO2 from bicarbonate buffer solutions… read more here.
Keywords: system; floating lid; method; bicarbonate buffer ... See more keywords
Improved prediction of in vivo supersaturation and precipitation of poorly soluble weakly basic drugs using a biorelevant bicarbonate buffer in a GI transfer model.
Sign Up to like & getrecommendations! Published in 2019 at "Molecular pharmaceutics"
DOI: 10.1021/acs.molpharmaceut.9b00534
Abstract: The characterization of intestinal dissolution of poorly soluble drugs represents a key task during development of both new drug candidates and drug products. The bicarbonate buffer is considered as the most biorelevant buffer for simulating… read more here.
Keywords: transfer model; model; bicarbonate buffer; precipitation ... See more keywords