N-Chlorinative Ring Contraction of 1,4-Dimethoxyphthalazines via a Bicyclization/Ring-Opening Mechanism
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DOI: 10.1055/s-0040-1706639
Abstract: An unprecedented N-chlorinative ring contraction of 1,2-diazines was discovered and investigated with an electrophilic chlorinating reagent, trichloroisocyanuric acid (TCICA). Through optimization and mechanistic analysis, the assisting role of n-Bu4NCl as an exogenous nucleophile was identified,… read more here.
Keywords: ring opening; opening mechanism; chlorinative ring; bicyclization ring ... See more keywords