Hetaryl-substituted bicyclo[1.1.1]pentanes (microreview)
Sign Up to like & getrecommendations! Published in 2019 at "Chemistry of Heterocyclic Compounds"
DOI: 10.1007/s10593-019-02558-7
Abstract: Synthesis and properties of heterocycles bearing bicyclo[1.1.1]pentane moiety attached to the heterocyclic ring are summarized in this microreview. In particular, heterocyclizations with bicyclo-[1.1.1]pentane derivatives, as well as reactions involving incorporation of the preexisting heterocyclic system… read more here.
Keywords: bicyclo pentanes; bicyclo pentane; hetaryl substituted; substituted bicyclo ... See more keywords
Radical Acylation of [1.1.1]Propellane with Aldehydes: Synthesis of Bicyclo[1.1.1]pentane Ketones.
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DOI: 10.1021/acs.orglett.2c01707
Abstract: Bicyclo[1.1.1]pentanes (BCPs) are widely utilized in drug design as sp3-rich bioisosteres for tert-butyl, internal alkynes, and aryl groups. A general and mild method for radical acylation of [1.1.1]propellane with aldehydes has been developed. The protocol… read more here.
Keywords: acylation propellane; propellane aldehydes; bicyclo pentane; pentane ketones ... See more keywords
Visible light-induced synthesis of 1,3-disubstituted bicyclo[1.1.1]pentane ketones via cooperative photoredox and N-heterocyclic carbene catalysis
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DOI: 10.1039/d3gc00643c
Abstract: Visible light-induced highly efficient synthesis of 1,3-disubstituted bicyclo[1.1.1]pentane with mild conditions, high atom economy, and superior functional group tolerance. read more here.
Keywords: synthesis disubstituted; light induced; disubstituted bicyclo; bicyclo pentane ... See more keywords