LAUSR

About LAUSR
Donate
Contact Us

Follow us:

You are not signed in:

Sign Up!


   Articles with "bicyclo pentanes" as a keyword



Photo by yapics from unsplash

Hetaryl-substituted bicyclo[1.1.1]pentanes (microreview)

Sign Up to like & get
recommendations! Published in 2019 at "Chemistry of Heterocyclic Compounds"

DOI: 10.1007/s10593-019-02558-7

Abstract: Synthesis and properties of heterocycles bearing bicyclo[1.1.1]pentane moiety attached to the heterocyclic ring are summarized in this microreview. In particular, heterocyclizations with bicyclo-[1.1.1]pentane derivatives, as well as reactions involving incorporation of the preexisting heterocyclic system… read more here.

Keywords: bicyclo pentanes; bicyclo pentane; hetaryl substituted; substituted bicyclo ... See more keywords
Photo by milada_vigerova from unsplash

Synthesis of selenoether and thioether functionalized bicyclo[1.1.1]pentanes

Sign Up to like & get
recommendations! Published in 2020 at "Tetrahedron"

DOI: 10.1016/j.tet.2020.131692

Abstract: Abstract Bicyclo[1.1.1]pentane is widely recognized as the bioisostere for aryl, tert-butyl, and internal alkynes. Herein we report an efficient and practical method for the preparation of selenoether and thioether functionalized bicyclo[1.1.1]pentanes from selenosulfonates/thiosulfonates and propellane.… read more here.

Keywords: bicyclo pentanes; selenoether thioether; functionalized bicyclo; thioether functionalized ... See more keywords

Synthesis of Sulfur-Substituted Bicyclo[1.1.1]pentanes by Iodo-Sulfenylation of [1.1.1]Propellane

Sign Up to like & get
recommendations! Published in 2022 at "Organic Letters"

DOI: 10.1021/acs.orglett.2c02875

Abstract: Thiols easily react with [1.1.1]propellane to give sulfur-substituted bicyclo[1.1.1]pentanes in radical reactions, but this reactivity is not replicated in the case of heterocyclic thiols. Herein, we address this issue by electrophilically activating [1.1.1]propellane to promote… read more here.

Keywords: bicyclo pentanes; iodo sulfenylation; sulfur substituted; substituted bicyclo ... See more keywords
Photo by 978lp from unsplash

Skeletal Editing Approach to Bridge-Functionalized Bicyclo[1.1.1]pentanes from Azabicyclo[2.1.1]hexanes.

Sign Up to like & get
recommendations! Published in 2023 at "Journal of the American Chemical Society"

DOI: 10.1021/jacs.3c02616

Abstract: Azabicyclo[2.1.1]hexanes (aza-BCHs) and bicyclo[1.1.1]pentanes (BCPs) have emerged as attractive classes of sp3-rich cores for replacing flat, aromatic groups with metabolically resistant, three-dimensional frameworks in drug scaffolds. Strategies to directly convert, or "scaffold hop", between these… read more here.

Keywords: bicyclo pentanes; skeletal editing; approach bridge; azabicyclo hexanes ... See more keywords
Photo by vlisidis from unsplash

Synthesis and applications of highly functionalized 1-halo-3-substituted bicyclo[1.1.1]pentanes† †Electronic supplementary information (ESI) available. CCDC 1825056–1825060. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c8sc01355a

Sign Up to like & get
recommendations! Published in 2018 at "Chemical Science"

DOI: 10.1039/c8sc01355a

Abstract: A wide range of halogenated bicyclo[1.1.1]pentanes are accessed by functional group tolerant radical ring-opening of tricyclo[1.1.1.01,3]pentane, using triethylborane as initiator. read more here.

Keywords: halo substituted; bicyclo pentanes; functionalized halo; applications highly ... See more keywords