A Single Enzyme in Enantiocomplementary Synthesis of β‐Nitroalcohols: Bidirectional Catalysis by Hydroxynitrile Lyase
Sign Up to like & getrecommendations! Published in 2024 at "ChemBioChem"
DOI: 10.1002/cbic.202400618
Abstract: A single enzyme, Baliospermum montanum hydroxynitrile lyase (BmHNL), without alteration, enabled bidirectional catalysis in enantiocomplementary synthesis of chiral β‐nitroalcohols. BmHNL catalyzed promiscuous Henry (24 examples) and retro‐Henry reaction (22 examples) provided up to >99 % and… read more here.
Keywords: hydroxynitrile lyase; bidirectional catalysis; synthesis; single enzyme ... See more keywords